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Special Issue "Marine Drugs Interact with Functional Proteins"

A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: 31 May 2018

Special Issue Editor

Guest Editor
Prof. Masaki Kita

Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan
Website | E-Mail
Interests: Natural products; Biologically and physiologically intriguing phenomena; Spectoscopic analysis; Target identification; Mode of action

Special Issue Information

Dear Colleagues,

It has been shown that a number of marine natural products interact with functional proteins to show potent biological and physiological activities. For example, an anticancer drug, eribulin, derived from the marine macrolide halichondrin B, is a unique inhibitor of microtubule dynamics. Some marine natural products have recently been shown to induce or inhibit protein‒protein interactions. These new mechanistic findings should be useful for the design and development of new pharmacological tools and therapeutic agents.

This Special Issue will highlight the progress in the following topics: Isolation and structures of bioactive marine natural products (such as anti-tumor, anti-bacterial, anti-inflammation, anti-oxidant compounds) that target functional proteins; development and use of chemical probes inspired from bioactive marine natural products; target protein identification and mechanism of action studies; structural and kinetic analysis of protein–ligand interactions; and structure-activity relationship studies and drug discovery study of marine bioactive compounds that interfere in protein dynamics.

Prof. Masaki Kita
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Marine natural products
  • Bioactive secondary metabolites
  • Target protein identification
  • Mechanism of action
  • Interference toward protein dynamics including protein–protein interaction
  • Structural and kinetic analysis of protein–ligand interactions
  • Structure-activity relationships
  • Drug discovery

Published Papers

This special issue is now open for submission.
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