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Special Issue "From Bioactive Compounds to New Drugs: Commemorative Issue Dedicated to Professor Ernesto Fattorusso (1937-2012)"

A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: 31 July 2018

Special Issue Editors

Guest Editor
Prof. Dr. Patrizia Ciminiello

Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli "Federico II", Via D. Montesano 49, I-80131 Napoli, Italy
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Fax: +39 081 678552
Interests: marine natural products; marine plankton; structure elucidation; marine biotoxins; dinoflagellates
Guest Editor
Prof. Dr. Alfonso Mangoni

Department of Pharmacy, University of Naples Federico II, Italy
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Interests: marine natural products; structural elucidation; biosynthetic gene clusters; metagenomics; computational chemistry
Guest Editor
Prof. Dr. Marialuisa Menna

Department of Pharmacy, University of Naples Federico II, Italy
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Interests: marine natural products; structure elucidation; stereochemistry; tunicates
Guest Editor
Prof. Orazio Taglialatela-Scafati

Department of Pharmacy, University of Naples Federico II, Italy
Website | E-Mail
Interests: marine and terrestrial natural products; pharmaceutical biology; stereostructure elucidation; bioactivity

Special Issue Information

Dear Colleagues,

Marine Drugs and Molecules are pleased to announce a joint commemorative Special Issue dedicated to Professor Ernesto Fattorusso, on the occasion of his 80th birthday in 2017, for his outstanding contribution in the research field of bioactive natural products.

Prof. Fattorusso (born in 1937) has been Professor of Organic Chemistry at the University of Naples Federico II since 1975. He was one of the founding fathers of the chemistry of marine natural products, and, more recently, he was also involved in the investigation of therapeutically active terrestrial plants of the Mediterranean flora. His prolific scientific activity is documented by more than 350 papers describing the isolation and identification of bioactive natural products, potential leads for drug, cosmetic, and biotechnological applications. Prof. Fattorusso founded a multidisciplinary research group, the NeaNat group, based at the Department of Pharmacy of the University of Naples Federico II, which will be continuing to work on these topics.

Since 1980, Prof. Fattorusso has coordinated many national and international projects (NOMATEC, BIOTOXmarin, NatPharma, BLUEGENICS among others) and established fruitful collaborations with several institutions around the world. Prof. Fattorusso has received a remarkable number of awards, including the prestigious Paul Scheuer Award in 2010 for his studies in the field of marine natural products: he was the first European scientist to receive this award.

This commemorative issue welcomes submission of previously unpublished manuscripts (original researches or reviews) on the investigation of biologically active chemical entities, with particular regard to natural products isolated from plants, marine invertebrates and microorganisms, potentially useful as lead compounds for the development of new drugs or biological tools.

We plan to receive submissions from November 2016 to the end of September 2017. Manuscripts will be published on an ongoing basis after being processed.

Prof. Dr. Patrizia Ciminiello
Prof. Dr. Alfonso Mangoni
Prof. Dr. Marialuisa Menna
Prof. Dr. Orazio Taglialatela-Scafati
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Lead compounds
  • Natural products
  • Biological tools
  • Drug development
  • Structure elucidation-
  • Organic synthesis

Related Special Issue

Published Papers (1 paper)

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Review

Open AccessFeature PaperReview Marine Pharmacology in 2012–2013: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, and Antiviral Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action
Mar. Drugs 2017, 15(9), 273; doi:10.3390/md15090273
Received: 20 July 2017 / Revised: 17 August 2017 / Accepted: 21 August 2017 / Published: 29 August 2017
PDF Full-text (4504 KB) | HTML Full-text | XML Full-text
Abstract
The peer-reviewed marine pharmacology literature from 2012 to 2013 was systematically reviewed, consistent with the 1998–2011 reviews of this series. Marine pharmacology research from 2012 to 2013, conducted by scientists from 42 countries in addition to the United States, reported findings on the
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The peer-reviewed marine pharmacology literature from 2012 to 2013 was systematically reviewed, consistent with the 1998–2011 reviews of this series. Marine pharmacology research from 2012 to 2013, conducted by scientists from 42 countries in addition to the United States, reported findings on the preclinical pharmacology of 257 marine compounds. The preclinical pharmacology of compounds isolated from marine organisms revealed antibacterial, antifungal, antiprotozoal, antituberculosis, antiviral and anthelmitic pharmacological activities for 113 marine natural products. In addition, 75 marine compounds were reported to have antidiabetic and anti-inflammatory activities and affect the immune and nervous system. Finally, 69 marine compounds were shown to display miscellaneous mechanisms of action which could contribute to novel pharmacological classes. Thus, in 2012–2013, the preclinical marine natural product pharmacology pipeline provided novel pharmacology and lead compounds to the clinical marine pharmaceutical pipeline, and contributed significantly to potentially novel therapeutic approaches to several global disease categories. Full article
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