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Special Issue "Seaweeds and Their Biological Actions"

A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: 30 June 2018

Special Issue Editors

Guest Editor
Prof. Herminia Domínguez

Universidad de Vigo, Spain
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Interests: solvent extraction; bioactives; biomass
Guest Editor
Dr. Stefan Kraan

Ireland
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Interests: seaweed; cultivation; bioactives; health promotion

Special Issue Information

Dear Colleagues,

Seaweeds are only partly explored, but their great diversity and complexity of metabolites, induced by the extreme environmental conditions, offer a unique and exclusive source of renewable bioactives.

Fractions, extracts, and purified compounds from marine macroalgae present high potential as preventing and therapeutic agents against several diseases, for their anticancer, anti-inflammatory, antiviral, antibacterial, anticoagulant properties, and for their immunomodulatory and neuroprotective capacities.

This Special Issue is aimed at presenting the updated information on the well-documented major biological actions relevant for medical and pharmaceutical applications that the compounds isolated from seaweed can offer.

As Guest Editors, we invite scientists to submit their latest research findings in this area, in relation to the biological activities, mechanisms of action and the formulation of novel products

Prof. Herminia Dominguez
Dr. Stefan Kraan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • seaweed
  • neuroprotection
  • inmunomodulation
  • antitumor
  • antimicrobial
  • anti-inflammatory

Published Papers (1 paper)

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Research

Open AccessArticle 3-Bromo-4,5-dihydroxybenzaldehyde Enhances the Level of Reduced Glutathione via the Nrf2-Mediated Pathway in Human Keratinocytes
Mar. Drugs 2017, 15(9), 291; doi:10.3390/md15090291
Received: 22 July 2017 / Revised: 23 August 2017 / Accepted: 15 September 2017 / Published: 18 September 2017
PDF Full-text (2700 KB) | HTML Full-text | XML Full-text
Abstract
A natural bromophenol found in seaweeds, 3-bromo-4,5-dihydroxybenzaldehyde (BDB), has been shown to possess antioxidant effects. This study aimed to investigate the mechanism by which BDB protects skin cells subjected to oxidative stress. The effect of BDB on the protein and mRNA levels of
[...] Read more.
A natural bromophenol found in seaweeds, 3-bromo-4,5-dihydroxybenzaldehyde (BDB), has been shown to possess antioxidant effects. This study aimed to investigate the mechanism by which BDB protects skin cells subjected to oxidative stress. The effect of BDB on the protein and mRNA levels of glutathione-related enzymes and the cell survival of human keratinocytes (HaCaT cells) was investigated. BDB treatment increased the protein and mRNA levels of glutathione synthesizing enzymes and enhanced the production of reduced glutathione in HaCaT cells. Furthermore, BDB activated NF-E2-related factor 2 (Nrf2) and promoted its localization into the nucleus by phosphorylating its up-stream signaling proteins, extracellular signal–regulated kinase and protein kinase B. Thus, BDB increased the production of reduced glutathione and established cellular protection against oxidative stress via an Nrf2-mediated pathway. Full article
(This article belongs to the Special Issue Seaweeds and Their Biological Actions)
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