Special Issue "Mechanism of Action of Marine and Freshwater Toxins"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (15 June 2018)
Prof. Aurelia Tubaro
Dept. Life Sciences-B Building, University of Trieste, Via A. Valerio, 6, 34127 Trieste, Italy
Interests: toxicology of natural compounds; pharmacology of natural compounds; nanotoxicology; palytoxins; development of assays for toxins
Many marine and freshwater toxins provoke human threats after oral ingestion of contaminated food and seafood, some of them lethal, as well as after inhalation, cutaneous, and/or ocular exposure. In fact, marine and freshwater organisms, such as cyanobacteria, diatoms, and dinoflagellates, can produce secondary metabolites, peculiar for their structures, which are sometimes very complex and difficult to reproduce in laboratory. Similarly, their mechanisms of actions are often different from those of the common synthetized molecules, opening new possibilities for understanding key processes of molecular mechanisms not yet completely clarified. In fact, some of these compounds are currently used as biochemical tools (i.e., okadaic acid), as well as lead compounds to develop new drugs for therapeutic purposes (i.e., brevetoxins).
Another important point related to the mechanism of action of these toxin is the possibility to develop functional assays to quantify them directly in seafood and/or in the producing organisms, at concentrations directly related to their toxic potential. In addition, gaining new insights into the mechanism of action of these compounds can be instrumental to develop the relevant clinical approach for poisoned people.
Prof. Aurelia Tubaro
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- mechanism of action
- functional assays
- okadaic acid
- ciguatera toxins