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Special Issue "Marine Small-Molecule Bioactive Agents and Therapeutic Targets"

A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: 30 September 2018

Special Issue Editor

Guest Editor
Prof. Enrique Barrajón-Catalán

Universidad Miguel Hernández, Instituto de Biología Molecular y Celular, Av. Univ S/N, E-03202 Elche, Spain
Website | E-Mail
Interests: natural compounds; polyphenols; marine compounds; cancer; antimicrobial

Special Issue Information

Dear colleagues:

Nowadays, at least one-third of the current top-twenty drugs on the market are derived from a natural source, and approximately 50% of the marketed drugs are classified as naturally-derived or are designed on the basis of natural compounds. Marine biodiversity is huge and is correlated with a wide chemical diversity in their compounds, most of them still unknown or uncharacterized. In fact, it is estimated that only 18% of marine natural products have been discovered so far compared with products of terrestrial organisms.

Small molecules, such as small peptides, polyphenols and terpenoids, are especially interesting due their particular pharmacological and pharmacokinetic properties. This Special Issue is focused in these small molecules from marine origin with special interest in the following topics:

  • New small molecules with pharmacological activity and their molecular targets.
  • Anticancer, antimicrobial and antinflammatory small marine molecules.Use of small marine compounds in other diseases.
  • Use in cosmetic, cosmoceutic and nutraceutic products.
  • Purification, chemical characterization  and structural elucidation.
  • In silico virtual screenings and HTS studies.
  • Pharmakokinetics and bioavailability studies.
  • Preclinical and clinical trials.

The aim of this Special Issue is to collect literature that reflect the actual state-of-the-art and increase our knowledge about marine small molecules and their biological activities.

As Guest Editor of this Special Issue, I cordially invite researchers from all around the world to contribute to this Special Issue by submitting original research articles, long and mini review papers, short notes, and opinions according to their expertise.

Prof. Enrique Barrajón-Catalán
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • marine product
  • small molecule
  • polyphenol
  • peptide
  • cancer
  • antimicrobial
  • antiinflammatory

Published Papers

This special issue is now open for submission.

Journal Contact

Marine Drugs Editorial Office
St. Alban-Anlage 66, 4052 Basel, Switzerland
Tel. +41 61 683 77 34
Fax: +41 61 302 89 18
Editorial Board
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