Special Issue "Biocompatibility of Biomaterials"

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A special issue of Journal of Functional Biomaterials (ISSN 2079-4983).

Deadline for manuscript submissions: closed (30 June 2012)

Special Issue Editor

Guest Editor
Prof. Dr. Paul V. Hatton
School of Clinical Dentistry, University of Sheffield, 19 Claremont Crescent, Sheffield S10 2TA, UK
Website: http://www.sheffield.ac.uk/dentalschool/staff/profiles/hatton
E-Mail: paul.hatton@sheffield.ac.uk
Phone: +44 114 271 7938
Fax: +44 114 226 5484
Interests: biomaterials, medical devices and tissue engineering for clinical applications in human skeletal tissues

Special Issue Information

Dear Colleagues,

The concept of "biocompatibility" underpins all of the development and application of biomaterials, as materials that are not safe and fit for their intended purpose are clearly unsuitable for clinical use. With the increasing use of biomaterials and related technologies that interact with host tissues to achieve a performance benefit, the evaluation of biocompatibility is becoming both more important and more challenging. Indeed, the combination of newly-available medical technologies and increased need for cost-effective clinical intervention is driving unprecedented change in biomaterials science, and there is today a greater need than ever before to develop good predictive models of biocompatibility. In vitro testing is now often very complex, with the development of co-cultured cell constructs and bioreactors that can mimic some of the complexity of the whole organism. In vivo models too have increased in sophistication, with genetically engineered animals that can communicate specific physiological changes via detectable signals such as fluorescence. Finally, many new analytical technologies, for example Raman microscopy, are being adopted from other fields and applied to the study of biochemical events that are related closely to biocompatibility. The aim of this special issue is to consider all aspects of biocompatibility testing, with a particular emphasis on the development and use of new technologies for this purpose.

Prof. Dr. Paul V. Hatton
Guest Editor

Keywords

  • biocompatibility
  • in vitro testing
  • in vivo testing
  • co-culture
  • bioreactor

Published Papers (10 papers)

J. Funct. Biomater. 2012, 3(4), 864-878; doi:10.3390/jfb3040864
Received: 26 July 2012; in revised form: 12 October 2012 / Accepted: 22 October 2012 / Published: 5 December 2012
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J. Funct. Biomater. 2012, 3(4), 839-863; doi:10.3390/jfb3040839
Received: 27 June 2012; Accepted: 24 October 2012 / Published: 15 November 2012
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J. Funct. Biomater. 2012, 3(4), 776-798; doi:10.3390/jfb3040776
Received: 20 June 2012; in revised form: 25 September 2012 / Accepted: 24 October 2012 / Published: 14 November 2012
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J. Funct. Biomater. 2012, 3(4), 706-725; doi:10.3390/jfb3040706
Received: 19 April 2012; in revised form: 12 July 2012 / Accepted: 27 September 2012 / Published: 16 October 2012
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J. Funct. Biomater. 2012, 3(3), 615-641; doi:10.3390/jfb3030615
Received: 26 June 2012; in revised form: 3 August 2012 / Accepted: 21 August 2012 / Published: 17 September 2012
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J. Funct. Biomater. 2012, 3(3), 569-587; doi:10.3390/jfb3030569
Received: 29 June 2012; in revised form: 1 August 2012 / Accepted: 6 August 2012 / Published: 14 August 2012
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J. Funct. Biomater. 2012, 3(3), 514-527; doi:10.3390/jfb3030514
Received: 28 June 2012; in revised form: 20 July 2012 / Accepted: 20 July 2012 / Published: 2 August 2012
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J. Funct. Biomater. 2012, 3(3), 497-513; doi:10.3390/jfb3030497
Received: 15 June 2012; in revised form: 19 July 2012 / Accepted: 20 July 2012 / Published: 27 July 2012
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J. Funct. Biomater. 2012, 3(2), 327-348; doi:10.3390/jfb3020327
Received: 7 February 2012; in revised form: 21 March 2012 / Accepted: 11 April 2012 / Published: 25 April 2012
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abstract graphic

J. Funct. Biomater. 2012, 3(2), 225-238; doi:10.3390/jfb3020225
Received: 2 December 2011; in revised form: 23 February 2012 / Accepted: 12 March 2012 / Published: 23 March 2012
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Last update: 26 February 2014

J. Funct. Biomater. EISSN 2079-4983 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert