Special Issue "Wound Healing and Tissue Regeneration"
A special issue of Journal of Developmental Biology (ISSN 2221-3759).
Deadline for manuscript submissions: 31 December 2014
Dr. Robin C. Muise-Helmericks
Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston SC, 29425, USA
Interests: Akt family of kinases; angiogenesis; wound healing; mitochondrial function and control
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Developmental Biology is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Observations on lumbar spinal cord recovery after lesion in lizard indicates regeneration of a cellular and fibrous bridge reconnecting the injured cord
Author: Alibardi Lorenzo
Affiliations: Comparative Histolab and Department of Bigea, University of Bologna, Italy; Dipartimento di Biologia, Geologia e Scienze Ambientali, University of Bologna, via Selmi 3, 40126, Bologna, Italy; E-Mail: Alibardi@biblio.cib.unibo.it; Tel.: +39 051 209 4141; Fax: +39 051 209 4286
Abstract: The lumbar spinal cord of lizards was transected but after the initial paralysis most lizards recovered un-coordinated movements of hind limbs. At 25-45 days post-lesion about 50% of lizards were capable of walking with a limited coordination. Histological analysis showed that the spinal cord was transected and the ependyma of the central canal formed two enlargements to seal the proximal and distal ends of the severed spinal cord. Glial and few small neurons were formed while bridge axons crossed the gap between the proximal and the distal stumps of the transected spinal cord as it was confirmed by retrograde tract-tracing technique. The bridging fibers derived from interneurons located in the central and dorsal grey matter of the proximal spinal cord stump suggesting they belong to the local central locomotory pattern generator circuit. The limited recovery of hind limb movements may derive from the regeneration of short proprio-spinal axons joining the two stumps of the spinal cord. This suggests that lizards may produce insights on the molecular conditions for making a permissive environment favoring nerve regeneration.
Last update: 22 October 2014