Special Issue "UV-Induced Cell Death"
Deadline for manuscript submissions: closed (15 September 2011)
Prof. Dr. Terrence Piva
School of Medical Sciences RMIT University PO Box 71 Bundoora Victoria 3083 Australia
Phone: Office +61 3 9925 6503; Lab 9925 7278
Fax: +61 3 9925 7063
Interests: cell death; photobiology; photoimmunology; skin cancer; enzymology; cell metabolism; oxidative stress; cancer metabolism; cell signalling; cytokines; inflammation; enzyme kinetics; metal oxide nanoparticles; sunscreens
When we think of UV radiation we imagine getting a suntan, and sometimes when we are in the sun too long we end up getting sunburnt. Sunburnt skin cells are those, which undergo apoptosis as a result of UV exposure. Other cells in the skin can undergo necrosis. The mechanisms by which UVA, UVB and UVC trigger cell death in different cells differs depending on the cell line examined and the dose and type of UV that is used. This issue will look at the effects UV radiation has on cell death, looking at but not restricted to changes in the activity of intracellular signalling pathways, caspase activation, membrane damage, production of ROS or via direct nuclear damage and the effect this has on the cell as it dies. An often asked question is “does a cell undergoing apoptosis release molecules which may influence those around it”, hopefully this issue may help shed light on this question. For instance does a dying cell release enzymes of growth factors, which may stimulate adjacent cells to undergo cell division to replace lost cells? It is unclear if this occurs in the skin when cells are exposed to too much sunlight. I encourage you to submit a manuscript to this issue and help shed further “light” on the lethal effects UV radiation have on cells.
Prof. Dr. Terrence Piva
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- ultraviolet light
- cell membrane
- signalling pathways
- enzyme activation
- sunburnt cell
Int. J. Mol. Sci. 2011, 12(11), 8063-8085; doi:10.3390/ijms12118063
Received: 14 September 2011; in revised form: 5 October 2011 / Accepted: 31 October 2011 / Published: 17 November 2011| Download PDF Full-text (708 KB) | Download XML Full-text
Article: Coenzyme Q10 Ameliorates Ultraviolet B Irradiation Induced Cell Death Through Inhibition of Mitochondrial Intrinsic Cell Death Pathway
Int. J. Mol. Sci. 2011, 12(11), 8302-8315; doi:10.3390/ijms12118302
Received: 23 August 2011; in revised form: 8 October 2011 / Accepted: 21 November 2011 / Published: 24 November 2011| Download PDF Full-text (1994 KB) | Download XML Full-text
Article: Caffeine Abolishes the Ultraviolet-Induced REV3 Translesion Replication Pathway in Mouse Cells
Int. J. Mol. Sci. 2011, 12(12), 8513-8529; doi:10.3390/ijms12128513
Received: 16 September 2011; in revised form: 8 November 2011 / Accepted: 17 November 2011 / Published: 29 November 2011| Download PDF Full-text (2108 KB) | Download XML Full-text
Int. J. Mol. Sci. 2011, 12(12), 8947-8960; doi:10.3390/ijms12128947
Received: 11 October 2011; in revised form: 15 November 2011 / Accepted: 30 November 2011 / Published: 6 December 2011| Download PDF Full-text (327 KB) | Download XML Full-text
Review: Protein Kinases and Transcription Factors Activation in Response to UV-Radiation of Skin: Implications for Carcinogenesis
Int. J. Mol. Sci. 2012, 13(1), 142-172; doi:10.3390/ijms13010142
Received: 20 November 2011; in revised form: 14 December 2011 / Accepted: 16 December 2011 / Published: 23 December 2011| Download PDF Full-text (429 KB) | Download XML Full-text
Article: Ultraviolet C Irradiation Induces Different Expression of Cyclooxygenase 2 in NIH 3T3 Cells and A431 Cells: The Roles of COX-2 Are Different in Various Cell Lines
Int. J. Mol. Sci. 2012, 13(4), 4351-4366; doi:10.3390/ijms13044351
Received: 1 February 2012; in revised form: 5 March 2012 / Accepted: 16 March 2012 / Published: 5 April 2012| Download PDF Full-text (466 KB) | Download XML Full-text
Last update: 26 September 2012