Special Issue "Protein Folding 2015"

Quicklinks

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry, Molecular Biology and Biophysics".

Deadline for manuscript submissions: 19 June 2015

Special Issue Editor

Guest Editor
Prof. Dr. Salvador Ventura
Protein Folding and Conformational Diseases Lab (PFCD), Dept. of Biochemistry and Molecular Biology, Institute of Biotechnology and Biomedicine, Parc de Recerca UAB, Mòdul B, Universitat Autònoma de Barcelona, E-08193 Bellaterra (Barcelona), Spain
Website: http://ibb.uab.cat/ibb/index.php?option=com_wrapper&Itemid=143&CodiGrup=36
E-Mail: salvador.ventura@uab.es
Interests: protein folding; protein misfolding and aggregation; protein-protein interactions

Special Issue Information

Dear Colleagues,

Protein folding is among the most complex and challenging processes in Biochemistry. It is accepted that, after the synthesis at the ribosome, most polypeptides must fold into their specific three-dimensional structures before they can exert any biological function. Only properly folded conformers can interact specifically with their molecular targets. Therefore, protein folding is central to many biological processes. It has long been known that the functional structure of a protein is coded by its primary one-dimensional amino acid sequence. Despite the molecular mechanisms behind the folding code are still not completely understood, it is also true that in recent years we have witnessed significant advances towards this goal, resulting from the development of new experimental approaches and sophisticated prediction methods, but specially arising from new ways of thinking about protein folding and dynamics. Folding within biomembranes, multi-domain protein folding, folding in the cell, molecular chaperone-assisted holding and the dynamics of intrinsically disordered proteins are among the newest and more active areas of research. Although protein folding and dynamics are behind virtually all cell reactions, ranging from transcription to motion, it is the link to human disease that has put this subject in the public eye, because protein misfolding and subsequent aggregation have been shown to be the cause underlying dozens of human disorders. It turns out that understanding and predicting protein folding would allow elucidating how misfolded proteins cause aggregation and cytotoxicity. Thus, in a scientific environment that promotes technology transfer and tends to leave basic since aside, it is encouraging to learn that first principles hold the clue for therapeutic intervention in devastating disorders such us Parkinson’s and Alzheimer’s diseases. 
The aim of this special issue is to illustrate, through selected works, frontier research in protein folding.

Prof. Dr. Salvador Ventura
Guest Editor

Submission

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF.

Keywords

  • amyloid
  • calorimetry
  • chaperones
  • crowding and folding
  • downhill folding
  • energy lanscape
  • folding in biomembranes
  • folding in the cell
  • folding intermediates
  • folding kinetics
  • intrinsically disordered proteins
  • molecular dynamics simulation of folding
  • oxidative folding
  • protein aggregation
  • protein folding and design
  • protein folding and docking
  • protein folding and evolution
  • protein misfolding
  • single molecule folding
  • transition state analysis

Published Papers (24 papers)

Download All Papers
Sort by:
Display options:
Select articles Export citation of selected articles as:
Select/unselect all
Displaying article 1-24
p. 22604-22617
by , , ,  and
Int. J. Mol. Sci. 2013, 14(11), 22604-22617; doi:10.3390/ijms141122604
Received: 1 October 2013; in revised form: 25 October 2013 / Accepted: 4 November 2013 / Published: 15 November 2013
Show/Hide Abstract | PDF Full-text (677 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 21339-21352
by , ,  and
Int. J. Mol. Sci. 2013, 14(11), 21339-21352; doi:10.3390/ijms141121339
Received: 31 August 2013; in revised form: 24 September 2013 / Accepted: 27 September 2013 / Published: 25 October 2013
Show/Hide Abstract | PDF Full-text (412 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 20635-20657
by  and
Int. J. Mol. Sci. 2013, 14(10), 20635-20657; doi:10.3390/ijms141020635
Received: 30 July 2013; in revised form: 17 September 2013 / Accepted: 19 September 2013 / Published: 15 October 2013
Show/Hide Abstract | PDF Full-text (545 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 19109-19127
by ,  and
Int. J. Mol. Sci. 2013, 14(9), 19109-19127; doi:10.3390/ijms140919109
Received: 7 August 2013; in revised form: 29 August 2013 / Accepted: 30 August 2013 / Published: 17 September 2013
Show/Hide Abstract | PDF Full-text (1061 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 19128-19145
by , ,  and
Int. J. Mol. Sci. 2013, 14(9), 19128-19145; doi:10.3390/ijms140919128
Received: 2 August 2013; in revised form: 28 August 2013 / Accepted: 30 August 2013 / Published: 17 September 2013
Show/Hide Abstract | PDF Full-text (906 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Protein Folding 2015)
abstract graphic
p. 18362-18384
by , , , , , , , , , , ,  and
Int. J. Mol. Sci. 2013, 14(9), 18362-18384; doi:10.3390/ijms140918362
Received: 6 June 2013; in revised form: 21 August 2013 / Accepted: 22 August 2013 / Published: 5 September 2013
Show/Hide Abstract | PDF Full-text (1436 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 17943-17957
by , , , , ,  and
Int. J. Mol. Sci. 2013, 14(9), 17943-17957; doi:10.3390/ijms140917943
Received: 2 July 2013; in revised form: 22 August 2013 / Accepted: 23 August 2013 / Published: 3 September 2013
Show/Hide Abstract | PDF Full-text (953 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
abstract graphic
p. 17830-17844
by ,  and
Int. J. Mol. Sci. 2013, 14(9), 17830-17844; doi:10.3390/ijms140917830
Received: 26 July 2013; in revised form: 7 August 2013 / Accepted: 26 August 2013 / Published: 30 August 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (1802 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 17256-17278
by ,  and
Int. J. Mol. Sci. 2013, 14(9), 17256-17278; doi:10.3390/ijms140917256
Received: 27 June 2013; in revised form: 27 July 2013 / Accepted: 30 July 2013 / Published: 22 August 2013
Show/Hide Abstract | PDF Full-text (3168 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
abstract graphic
p. 16685-16705
by ,  and
Int. J. Mol. Sci. 2013, 14(8), 16685-16705; doi:10.3390/ijms140816685
Received: 28 June 2013; in revised form: 1 August 2013 / Accepted: 7 August 2013 / Published: 13 August 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (1091 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 16058-16075
by ,  and
Int. J. Mol. Sci. 2013, 14(8), 16058-16075; doi:10.3390/ijms140816058
Received: 15 April 2013; in revised form: 22 July 2013 / Accepted: 29 July 2013 / Published: 2 August 2013
Show/Hide Abstract | PDF Full-text (841 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 14892-14907
by ,  and
Int. J. Mol. Sci. 2013, 14(7), 14892-14907; doi:10.3390/ijms140714892
Received: 26 April 2013; in revised form: 1 July 2013 / Accepted: 2 July 2013 / Published: 17 July 2013
Show/Hide Abstract | PDF Full-text (1137 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Protein Folding 2015)
p. 14287-14300
by , ,  and
Int. J. Mol. Sci. 2013, 14(7), 14287-14300; doi:10.3390/ijms140714287
Received: 23 April 2013; in revised form: 19 June 2013 / Accepted: 20 June 2013 / Published: 9 July 2013
Show/Hide Abstract | Cited by 3 | PDF Full-text (458 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 13194-13212
by , ,  and
Int. J. Mol. Sci. 2013, 14(7), 13194-13212; doi:10.3390/ijms140713194
Received: 2 May 2013; in revised form: 4 June 2013 / Accepted: 4 June 2013 / Published: 26 June 2013
Show/Hide Abstract | Cited by 2 | PDF Full-text (1159 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Protein Folding 2015)
p. 13282-13306
by , , , ,  and
Int. J. Mol. Sci. 2013, 14(7), 13282-13306; doi:10.3390/ijms140713282
Received: 22 April 2013; in revised form: 4 June 2013 / Accepted: 13 June 2013 / Published: 26 June 2013
Show/Hide Abstract | Cited by 2 | PDF Full-text (1514 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 12675-12695
by , , , ,  and
Int. J. Mol. Sci. 2013, 14(6), 12675-12695; doi:10.3390/ijms140612675
Received: 4 March 2013; in revised form: 10 May 2013 / Accepted: 4 June 2013 / Published: 17 June 2013
Show/Hide Abstract | PDF Full-text (772 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
abstract graphic
p. 12411-12457
by  and
Int. J. Mol. Sci. 2013, 14(6), 12411-12457; doi:10.3390/ijms140612411
Received: 19 April 2013; in revised form: 29 May 2013 / Accepted: 4 June 2013 / Published: 13 June 2013
Show/Hide Abstract | Cited by 7 | PDF Full-text (650 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 12157-12169
by  and
Int. J. Mol. Sci. 2013, 14(6), 12157-12169; doi:10.3390/ijms140612157
Received: 2 April 2013; in revised form: 29 April 2013 / Accepted: 14 May 2013 / Published: 6 June 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (1790 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 10896-10907
by  and
Int. J. Mol. Sci. 2013, 14(6), 10896-10907; doi:10.3390/ijms140610896
Received: 25 February 2013; in revised form: 24 April 2013 / Accepted: 24 April 2013 / Published: 24 May 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (1902 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Protein Folding 2015)
p. 10727-10748
by
Int. J. Mol. Sci. 2013, 14(6), 10727-10748; doi:10.3390/ijms140610727
Received: 1 April 2013; in revised form: 9 May 2013 / Accepted: 9 May 2013 / Published: 23 May 2013
Show/Hide Abstract | Cited by 4 | PDF Full-text (1421 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 9893-9905
by , , ,  and
Int. J. Mol. Sci. 2013, 14(5), 9893-9905; doi:10.3390/ijms14059893
Received: 7 March 2013; in revised form: 9 April 2013 / Accepted: 24 April 2013 / Published: 10 May 2013
Show/Hide Abstract | Cited by 3 | PDF Full-text (407 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
abstract graphic
p. 7795-7814
by ,  and
Int. J. Mol. Sci. 2013, 14(4), 7795-7814; doi:10.3390/ijms14047795
Received: 8 March 2013; in revised form: 27 March 2013 / Accepted: 1 April 2013 / Published: 10 April 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (1184 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Protein Folding 2015)
abstract graphic
p. 6241-6258
by , ,  and
Int. J. Mol. Sci. 2013, 14(3), 6241-6258; doi:10.3390/ijms14036241
Received: 18 February 2013; in revised form: 11 March 2013 / Accepted: 12 March 2013 / Published: 19 March 2013
Show/Hide Abstract | Cited by 4 | PDF Full-text (1822 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Protein Folding 2015)
p. 5284-5311
by , , , ,  and
Int. J. Mol. Sci. 2013, 14(3), 5284-5311; doi:10.3390/ijms14035284
Received: 8 January 2013; in revised form: 5 February 2013 / Accepted: 7 February 2013 / Published: 6 March 2013
Show/Hide Abstract | Cited by 3 | PDF Full-text (4307 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Protein Folding 2015)
abstract graphic
Select/unselect all
Displaying article 1-24
Select articles Export citation of selected articles as:

Last update: 15 September 2014

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert