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Special Issue "Selected Papers from 3-ISPMF, 3rd International Symposium on Phytochemicals in Medicine and Food (Kunming, 2018)"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 15 April 2018

Special Issue Editors

Guest Editor
Prof. Dr. Jianbo Xiao

Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau; College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China
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Interests: phytochemicals; polyphenols; diabetes; function food; natural products; glycosylation; biological activity; flavonoids; stilbenoids; pharmacokinetics; nutrition and metabolism; polyphenol-protein interaction
Guest Editor
Prof. Dr. Miron Anca

Dept. Pharmacognosy-Phytotherapy, Faculty of Pharmacy, University of Medicine and Pharmacy "Grigore T. Popa",Universitatii Street, No 16, 700115, Iasi, Romania
E-Mail
Interests: phytochemicals; natural products; plant biodiversity; medicinal plants; food plants; bioactivity; polyphenols; glucosinolates; biocides
Guest Editor
Prof. Dr. Yongliang Zhuang

Yunnan Institute of Food Safety, Kunming University of Science and Technology, Kunming, Yunnan, China
E-Mail
Interests: polysaccharides; peptide; natural products; function foods; biochemistry; nutrition; antioxidant agents and mechanisms; structure-activity relationships

Special Issue Information

Dear Colleagues,

This Special Issue is related to 3rd International Symposium on Phytochemicals in Medicine and Food (3-ISPMF), which will be held at the Kunming University of Science and Technology, 26–29 August, 2018. 3-ISPMF is sponsored by the Phytochemical Society of Europe (PSE), International Society for Chinese Medicine (ISCM), and the Phytochemical Society of Europe (PSA).

This Special Issue seeks updated and new knowledge on the phytochemicals in medicine and food. Evidence from epidemiological investigations shows that natural phytochemicals have received increased attention due to their considerable benefits in preventing and managing modern diseases, such as cancers, diabetes, and cardiovascular diseases. This Special Issue will shape the future research direction for this important phytomedicine source. Our purpose is to feature high quality advanced research and knowledge, contributed by various research groups around the world, working on phytochemicals. We invite researchers to contribute reviews and reports of their recent work on the chemistry, biology and biotechnology of phytochemicals.

The Special Issue will focus on the phytochemicals in medicine and food, and will include the following aspects:

  • Natural products for the prevention and therapy of modern diseases.
  • Mechanism of phytochemicals for therapy and chemoprevention of modern diseases.
  • Importance of natural phytochemicals in medicine and food
  • QSAR and modeling for natural drugs design.
  • Natural antioxidants and human health.
  • New strategy of using natural products for managing diseases
  • Pharmacokinetics and biotransformation of phytochemicals

Prof. Dr. Jianbo Xiao
Prof. Dr. Miron Anca
Prof. Dr. Yongliang Zhuang

Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Phytochemicals
  • Medicinal plants
  • Natural products
  • Food chemistry
  • Phytomedicine
  • Metabolism
  • Prevention
  • Chemoprevention
  • Function food
  • Pharmacokinetics
  • Biotransformation
  • Structure-activity relationships

Published Papers (3 papers)

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Research

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Open AccessArticle The Candida albicans Inhibitory Activity of the Extract from Papaya (Carica papaya L.) Seed Relates to Mitochondria Dysfunction
Int. J. Mol. Sci. 2017, 18(9), 1858; doi:10.3390/ijms18091858
Received: 26 July 2017 / Revised: 16 August 2017 / Accepted: 18 August 2017 / Published: 25 August 2017
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Abstract
The inhibitory activity of the papaya seed extract (PSE) on Candida albicans (C. albicans) was determined by turbidimetry method. The inhibitory mechanisms were also evaluated from the prospective of reactive oxygen species (ROS) generation, mitochondrial membrane potential (MMP) decrease, and the
[...] Read more.
The inhibitory activity of the papaya seed extract (PSE) on Candida albicans (C. albicans) was determined by turbidimetry method. The inhibitory mechanisms were also evaluated from the prospective of reactive oxygen species (ROS) generation, mitochondrial membrane potential (MMP) decrease, and the activities of four complex enzymes in mitochondria respiratory chain. Results obtained from this study indicated that the PSE exhibited an effective inhibitory activity on C. albicans and induced significant accumulation of ROS and collapse of MMP. The Complex I and Complex III exhibited continues significant decrease in mitochondrial enzyme activity assays, but the Complex II and Complex IV activities were not positively correlated. Furthermore, the GC-MS analysis demonstrated that the PSE represents a rich and high-purity source of benzyl isothiocyanate (BITC), which indicated the BITC may be responsible for the mitochondrial dysfunction. Full article
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Open AccessArticle GC-MS Fingerprinting Combined with Chemometric Methods Reveals Key Bioactive Components in Acori Tatarinowii Rhizoma
Int. J. Mol. Sci. 2017, 18(7), 1342; doi:10.3390/ijms18071342
Received: 16 May 2017 / Revised: 12 June 2017 / Accepted: 20 June 2017 / Published: 3 July 2017
PDF Full-text (1785 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
This present study aims to identify the key bioactive components in acorus tatarinowii rhizoma (ATR), a traditional Chinese medicine (TCM) with various bioactivities. Partial least squares regression (PLSR) was employed to describe the relationship between the radical scavenging activity and the volatile components.
[...] Read more.
This present study aims to identify the key bioactive components in acorus tatarinowii rhizoma (ATR), a traditional Chinese medicine (TCM) with various bioactivities. Partial least squares regression (PLSR) was employed to describe the relationship between the radical scavenging activity and the volatile components. The PLSR model was improved by outlier elimination and variable selection and was evaluated by 10-fold cross-validation and external validation in this study. Based on the PLSR model, eleven chemical components were identified as the key bioactive components by variable importance in projection. The final PLS regression model with these components has good predictive ability. The Q2 was 0.8284, and the root mean square error for prediction was 2.9641. The results indicated that the eleven components could be a pattern to predict the radical scavenging activity of ATR. In addition, we did not find any specific relationship between the radical scavenging ability and the habitat of the ATRs. This study proposed an efficient strategy to predict bioactive components using the combination of quantitative chromatography fingerprints and PLS regression, and has potential perspective for screening bioactive components in complex analytical systems, such as TCM. Full article
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Review

Jump to: Research

Open AccessReview A Review on Konjac Glucomannan Gels: Microstructure and Application
Int. J. Mol. Sci. 2017, 18(11), 2250; doi:10.3390/ijms18112250
Received: 26 August 2017 / Revised: 2 October 2017 / Accepted: 12 October 2017 / Published: 27 October 2017
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Abstract
Konjac glucomannan (KGM) has attracted extensive attention because of its biodegradable, non-toxic, harmless, and biocompatible features. Its gelation performance is one of its most significant characteristics and enables wide applications of KGM gels in food, chemical, pharmaceutical, materials, and other fields. Herein, different
[...] Read more.
Konjac glucomannan (KGM) has attracted extensive attention because of its biodegradable, non-toxic, harmless, and biocompatible features. Its gelation performance is one of its most significant characteristics and enables wide applications of KGM gels in food, chemical, pharmaceutical, materials, and other fields. Herein, different preparation methods of KGM gels and their microstructures were reviewed. In addition, KGM applications have been theoretically modeled for future uses. Full article
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