Special Issue "Vaccine Safety and Public Health"
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601).
Deadline for manuscript submissions: closed (31 December 2013)
Vaccines have been one of the most successful medical and public health interventions, preventing disease and saving health care costs. The safety standards for vaccines are very high given the near universal use of many vaccines, vaccines are used among children, pregnant women, and other vulnerable populations, and vaccines are given to prevent illness rather than to treat disease. Clinical trials conducted before licensure ensures that common and serious adverse reactions do not occur due to vaccination in the populations studied for products that are licensed and widely used. However, clinical trials cannot detect adverse reactions that are rare because of limits to sample size. It is difficult to study adverse health outcomes with delayed onset in clinical trials as follow-up of participants is limited. Additionally, vaccines are often used in populations excluded from clinical trials. Consequently, post-licensure vaccine safety surveillance and observational studies are often employed for these purposes. Often the full safety profile of a vaccine is not fully characterized until hundreds of thousands to millions of people are vaccinated and appropriate studies are conducted. When a vaccine is found to be associated with an adverse health outcome, it is often important to understand the biological mechanism(s) causing the adverse reaction. The science of vaccine safety is particularly important given the success of many vaccines in preventing disease and a change in public focus from the risks of disease to the risks from vaccines, coupled with misinformation abundantly available on the internet and at times perpetuated in the media. This supplement will focus on vaccine safety studies, including laboratory studies, animal studies, clinical trials, post-licensure studies, and investigations into biological mechanisms causing vaccine adverse reactions.
Dr. Daniel Salmon
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed Open Access monthly journal published by MDPI.
- adverse events following immunization
- vaccine adverse reactions
- vaccine safety
- immunization safety