Special Issue "Natural and Induced Pluripotency in Stem Cells"
A special issue of Genes (ISSN 2073-4425).
Deadline for manuscript submissions: closed (30 September 2010)
Dr. Paolo Cinelli
Center for Clinical Research, Clinic for Trauma Surgery, University Hospital Zurich, Sternwartstrasse 14, CH-8091 Zurich, Switzerland
Interests: transcriptomics; microarrays; gene expression analysis; genotyping; molecular genetics; mouse genetics; transgenic technologies; embryonic stem cells; pluripotency
Cellular pluripotency is one of the most fascinating and promising research fields in biomedical research. The recent discovery that ordinary cells following the introduction of a small number of genes can acquire stem cell behaviors opens a new door for stem cell research and its application to therapeutic discovery. The exhaustive understanding of the molecular pathways controlling pluripotency and cellular reprogramming is essential for the development of effective and safe approaches to reprogram somatic cells towards a pluripotent state.
This Special Issue of the Journal Genes aims at presenting recent research and developments on this very exciting topic. Reviews and original papers presenting data on embryonic and induced pluripotent stem cells are welcome for this Special Issue. Special interest will be given to reports on genes and/or pathways involved in the establishment and maintenance of natural and acquired pluripotency, in controlling the global and local chromatin organization in pluripotent cells, and in triggering reprogramming in somatic and adult stem cells.
Dr. Paolo Cinelli
- embryonic stem cells
- induced pluripotent stem cells
- self renewal
- cell differentiation
- gene expression regulation
- DNA methylation