Special Issue "Natural and Induced Pluripotency in Stem Cells"
A special issue of Genes (ISSN 2073-4425).
Deadline for manuscript submissions: closed (30 September 2010)
Dr. Paolo Cinelli
Center for Clinical Research, Clinic for Trauma Surgery, University Hospital Zurich, Sternwartstrasse 14, CH-8091 Zurich, Switzerland
Phone: +41 44 255 3678
Interests: transcriptomics; microarrays; gene expression analysis; genotyping; molecular genetics; mouse genetics; transgenic technologies; embryonic stem cells; pluripotency
Cellular pluripotency is one of the most fascinating and promising research fields in biomedical research. The recent discovery that ordinary cells following the introduction of a small number of genes can acquire stem cell behaviors opens a new door for stem cell research and its application to therapeutic discovery. The exhaustive understanding of the molecular pathways controlling pluripotency and cellular reprogramming is essential for the development of effective and safe approaches to reprogram somatic cells towards a pluripotent state.
This Special Issue of the Journal Genes aims at presenting recent research and developments on this very exciting topic. Reviews and original papers presenting data on embryonic and induced pluripotent stem cells are welcome for this Special Issue. Special interest will be given to reports on genes and/or pathways involved in the establishment and maintenance of natural and acquired pluripotency, in controlling the global and local chromatin organization in pluripotent cells, and in triggering reprogramming in somatic and adult stem cells.
Dr. Paolo Cinelli
- embryonic stem cells
- induced pluripotent stem cells
- self renewal
- cell differentiation
- gene expression regulation
- DNA methylation
Genes 2010, 1(1), 4-8; doi:10.3390/genes1010004
Received: 3 March 2010; Accepted: 4 March 2010 / Published: 9 March 2010| Download PDF Full-text (29 KB) | Download XML Full-text
Review: Programming Pluripotent Precursor Cells Derived from Xenopus Embryos to Generate Specific Tissues and Organs
Genes 2010, 1(3), 413-426; doi:10.3390/genes1030413
Received: 8 October 2010; in revised form: 21 October 2010 / Accepted: 5 November 2010 / Published: 18 November 2010| Download PDF Full-text (875 KB)
Genes 2011, 2(1), 81-106; doi:10.3390/genes2010081
Received: 18 November 2010; in revised form: 22 December 2010 / Accepted: 5 January 2011 / Published: 13 January 2011| Download PDF Full-text (483 KB) | Download XML Full-text
Genes 2011, 2(1), 107-130; doi:10.3390/genes2010107
Received: 26 November 2010; in revised form: 6 December 2010 / Accepted: 4 January 2011 / Published: 14 January 2011| Download PDF Full-text (510 KB) | Download XML Full-text
Genes 2011, 2(1), 229-259; doi:10.3390/genes2010229
Received: 18 December 2010; in revised form: 11 January 2011 / Accepted: 19 January 2011 / Published: 25 February 2011| Download PDF Full-text (671 KB) | Download XML Full-text
Review: The Role of the Leukemia Inhibitory Factor (LIF) — Pathway in Derivation and Maintenance of Murine Pluripotent Stem Cells
Genes 2011, 2(1), 280-297; doi:10.3390/genes2010280
Received: 27 January 2011; in revised form: 26 February 2011 / Accepted: 7 March 2011 / Published: 9 March 2011| Download PDF Full-text (506 KB) | Download XML Full-text
Last update: 25 February 2014