Special Issue "Plant Metabolic Engineering of High Value Bioactive Products"

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Plant Genetics and Genomics".

Deadline for manuscript submissions: 31 October 2018

Special Issue Editors

Guest Editor
Prof. Birger Lindberg Møller

Plant Biochemistry Laboratory and Center for Synthetic Biology, Department of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Copenhagen, Denmark
Website | E-Mail
Phone: +45 20433411
Interests: plant synthetic biology; specialized metabolites; cyanogenic glucosides; diterpenoids; phenylpropanoids; biosynthetic complexes; metabolons
Guest Editor
Dr. Tomas Laursen

Center for Synthetic Biology, Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen, 1871 Frederiksberg C, Copenhagen, Denmark
Website | E-Mail
Phone: +45 51303999
Interests: plant synthetic biology; specialized metabolites; cyanogenic glucosides; biosynthetic complexes; metabolons; structure function relationship; single molecule microscopy and spectroscopy

Special Issue Information

Dear Colleagues,

Specialized metabolites in plants play a key role in the ability of plants to adapt to biotic and abiotic environmental stresses, and constitute a treasure trove of small molecules that are used by humans, e.g., to improve health and as condiments, pigments and low calorie natural sweeteners in foods. They are an integrated part of daily life. The approaches of synthetic biology may be used to widen the access to these valuable constituents by offering more direct and sustainable production systems. Development of contained production in green heterologous hosts like green algae, cyanobacteria and mosses requires detailed knowledge of the genes and enzymes involved in their formation, understanding of the organization of the enzymes in efficient metabolic modules to configure metabolic highways and development of technologies for environmental benign of isolation of the product formed. Monooxygenases and associated electron donating redox proteins are some of the key enzymes involved in obtaining the diversity of specialized metabolites in plants. Plants and other photosynthetic organisms have the unique ability to convert solar energy into reducing equivalents and to utilize carbon dioxide from the air as their sole carbon source. Improved photosynthesis and direct coupling of the reducing power of photosystem I to enzyme modules catalyzing formation of specialized metabolites would facilitate channeling of sunlight towards production of high value chemically complex compounds. The modular nature of the biosynthetic pathways provides an option to use a combinatorial approach to direct and optimize the production of known and new-to-nature compounds. Hence, synthetic biology is emerging as a novel approach to design and engineer biological modules with desired functional properties.

We cordially invite researchers working actively within these fields to submit their original research or review manuscripts to this Special Issue on “Plant Metabolic Engineering of High Value Bioactive Products”.

Prof. Birger Lindberg Møller
Dr. Tomas Laursen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Synthetic biology
  • Specialized metabolites
  • Biosynthetic modules
  • Isolation of enzyme complexes
  • Metabolic engineering
  • Metabolic highways
  • Pathway flux analyses
  • Storage and possible involvement of biomolecular condensates
  • Photosynthesis
  • Light harvesting complexes
  • Reaction centers
  • Environmental benign isolation procedures
  • Plants
  • Cyanobacteria
  • Algae
  • Moss
  • Cytochromes P450
  • Oxidoreductases

Published Papers

This special issue is now open for submission.
Back to Top