Special Issue "In Vitro Diagnostics"


A special issue of Diagnostics (ISSN 2075-4418).

Deadline for manuscript submissions: closed (31 March 2015)

Special Issue Editor

Guest Editor
Dr. Sandeep Kumar Vashist
HSG-IMIT—Institut für Mikro-und Informationstechnik & Department of Microsystems Engineering (IMTEK), Georges-Koehler-Allee 103, 79100 Freiburg, Germany
Website: http://www.imtek.de/professuren/anwendungsentwicklung/mitarbeiter/team/Vashist
E-Mail: sandeep.kumar.vashist@hsg-imit.de
Interests: in vitro diagnostics; mobile healthcare; point-of-care devices; lab-on-a-chip; immunoassays

Special Issue Information

Dear Colleagues,

There have been tremendous advances in the field of in vitro diagnostics (IVD) during the last two decades, which have led to the development of new IVD technologies and devices. Apart from remarkable advances in biomolecular immobilization, conjugation and surface modification strategies, significant improvements have been made in conventional IVD formats, such as enzyme-linked immunosorbent assay (ELISA) and lateral flow assays. The surface plasmon resonance-based instruments have led to a plethora of real-time label-free assays and have been widely adopted in industries, academia and healthcare. On the other hand, microfluidics-based IVD assays and lab-on-a-chip diagnostic platforms have inculcated tremendous interest among researchers based on their numerous advantages that are apparent to the scientific community. The ongoing research efforts are focused on the integration of microfluidics with lab-on-a-chip, automation and multiplexing capabilities. The use of nanomaterials has further led to naked-eye and signal enhanced assays, which are paving way to interesting bioanalytical applications. The development of paper-based IVD assays will be highly useful for developing nations, due to the significantly reduced analysis cost. Various novel biosensors and assay formats have also been developed. The last few years have seen a dramatic change in the landscape of IVD based on the emergence of smartphones as a point-of-care diagnostic device. Several low-cost smartphone-based devices have been developed and a wide range of diagnostic assays and bioanalytical applications have been demonstrated. These devices hold tremendous potential for mobile Healthcare and personalized medicine. The coming years will witness breakthroughs in IVD that will pave way to next-generation of rapid, low-cost, analytically superior and robust assays and devices.

Dr. Sandeep Kumar Vashist
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.


  • in vitro diagnostics
  • immunoassays
  • lateral flow assays
  • nanomaterial-based assays
  • biomarkers
  • lab-on-a-chip
  • microfluidics
  • electrochemistry
  • biosensors
  • signal enhancement
  • surface plasmon resonance
  • microarrays
  • paper-based assays
  • smartphone-based devices
  • mobile healthcare
  • point-of-care
  • bioanalytical applications

Published Papers (5 papers)

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Displaying article 1-5
p. 27-60
by , ,  and
Diagnostics 2015, 5(1), 27-60; doi:10.3390/diagnostics5010027
Received: 12 August 2014 / Revised: 20 October 2014 / Accepted: 1 December 2014 / Published: 2 February 2015
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(This article belongs to the Special Issue In Vitro Diagnostics)
p. 165-180
by ,  and
Diagnostics 2014, 4(4), 165-180; doi:10.3390/diagnostics4040165
Received: 3 June 2014 / Revised: 11 September 2014 / Accepted: 20 October 2014 / Published: 20 November 2014
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(This article belongs to the Special Issue In Vitro Diagnostics)
p. 140-152
by ,  and
Diagnostics 2014, 4(4), 140-152; doi:10.3390/diagnostics4040140
Received: 8 May 2014 / Revised: 22 July 2014 / Accepted: 9 September 2014 / Published: 29 September 2014
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(This article belongs to the Special Issue In Vitro Diagnostics)
p. 104-128
by ,  and
Diagnostics 2014, 4(3), 104-128; doi:10.3390/diagnostics4030104
Received: 25 June 2014 / Revised: 24 July 2014 / Accepted: 8 August 2014 / Published: 18 August 2014
Show/Hide Abstract | Cited by 3 | PDF Full-text (3738 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue In Vitro Diagnostics)
p. 27-46
by ,  and
Diagnostics 2014, 4(2), 27-46; doi:10.3390/diagnostics4020027
Received: 26 February 2014 / Revised: 5 April 2014 / Accepted: 9 April 2014 / Published: 21 April 2014
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(This article belongs to the Special Issue In Vitro Diagnostics)
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Last update: 19 December 2014

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