Special Issue "Enzymes in Organic Synthesis"
A special issue of Catalysts (ISSN 2073-4344).
Deadline for manuscript submissions: closed (15 February 2014)
Prof. Dr. Anita Maguire
Department of Chemistry, University College Cork, College Road, Cork, Ireland
The art of organic synthesis rests entirely on the ability to effect transformations between compounds in a selective and effective manner with regio- and sterocontrol, in addition to chemoselectivity. Over the past two decades development of methods for asymmetric synthesis has been a major focus mainly due to the need to access and synthesise compounds destined for pharmaceutical application in enantiopure form. Use of enzymes in organic synthesis is a particularly powerful approach to effect transformations in a highly selective manner usually under mild reaction conditions. The key advantages include the excellent enantiocontrol which can be achieved in enzyme mediated transformations in addition to chemoselectivity which cannot be achieved through traditional organic reactions. Use of enzymes aligns very much with the Green Chemistry approach. Use of enzymes in organic solvents in addition to the traditional aqueous media has significant potential in organic synthesis; in addition designer enzymes complement and enhance the application of wild type enzymes providing broader substrate scope and enhanced selectivity.
Prof. Dr. Anita Maguire
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 300 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- asymmetric Synthesis
- green Chemistry
Article: Enantiocomplementary Preparation of (S)- and (R)-Arylalkylcarbinols by Lipase-Catalysed Resolution and Mitsunobu Inversion: Impact of Lipase Amount
Catalysts 2014, 4(3), 215-225; doi:10.3390/catal4030215
Received: 13 February 2014; in revised form: 4 April 2014 / Accepted: 23 May 2014 / Published: 26 June 2014| PDF Full-text (1203 KB) | HTML Full-text | XML Full-text
Catalysts 2014, 4(2), 186-195; doi:10.3390/catal4020186
Received: 14 February 2014; in revised form: 16 May 2014 / Accepted: 23 May 2014 / Published: 18 June 2014| PDF Full-text (1651 KB) | HTML Full-text | XML Full-text
Communication: Kinetic Isotope Effect of Prostaglandin H Synthase Exhibits Inverted Temperature Dependence
Catalysts 2014, 4(2), 174-185; doi:10.3390/catal4020174
Received: 28 February 2014; in revised form: 24 April 2014 / Accepted: 23 May 2014 / Published: 11 June 2014| PDF Full-text (2000 KB) | HTML Full-text | XML Full-text | Supplementary Files
Last update: 15 October 2013