Special Issue "Organ-specific Metastasis Formation"

Guest Editor
Dr. Peter Gassmann
Department of General and Visceral Surgery, University Hospital Muenster, Waldeyerstrasse 1, 48149 Münster, Germany
E-Mail:
Interests: gastrointestinal cancers; mechanisms of metastasis formation; tumor cell adhesion and migration; animal models; gastro-intestinal surgery; hepato-biliary surgery

Guest Editor
Prof. Dr. Jörg Haier
Comprehensive Cancer Center Muenster, International Patient Management, University Hospital Muenster, Waldeyerstr. 1, 48149 Muenster, Germany
Website: http://cccm.uni-muenster.de/
E-Mail:
Interests: gastraintestinal cancer; metastasis; cell adhesion; cell migration; chemotaxis

Dear Colleagues,

The development of secondary distant organ and lymph node metastasis has an extraordinary impact on the prognosis of patients with solid cancer. In most cases the advent of metastatic growth represents the turning point from a local, potentially curable, disease to a systemic non-curable situation. As a highly regulated process, metastasis formation follows a distinct, non-random pattern characteristic for each tumor entity.

Metastasis formation and strategies to prevent this lethal event in the progression of cancer is of fundamental interest for cancer science and patient care. For this special issue of 'Cancers', papers high-lightning cellular mechanisms of metastasis formation, genetic and epigenetic aspects associated with organ and tumor specific metastasis formation, as well as papers outlining experimental and clinical therapeutic concepts for anti-metastatic treatment are welcome. We especially encourage the submission of papers presenting innovative animal models of organ specific metastasis formation.

Dr. Peter Gassmann
Guest Editor

Submission Information

All manuscripts should be submitted to cancers@mdpi.org with a copy to the Guest Editor. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed Open Access monthly journal published by MDPI.

For the first two issues, to be published in 2009 and 2010, the Article Processing Charges (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.

• organ specific metastasis
• animal models
• anti-metastatic treatment
• metastasis (-suppressor) genes
• lymph nod metastasis