Special Issue "Breast Cancers: Pathology and Biomarkers"


A special issue of Cancers (ISSN 2072-6694).

Deadline for manuscript submissions: closed (30 October 2012)

Special Issue Editor

Guest Editor
Prof. Dr. Sandip Kumar SenGupta
Department of Pathology & Molecular Medicine, Queen's University, Canada
E-Mail: sengupts@kgh.kari.net
Phone: +1 613 549 6666 ext. 4164
Fax: +1 613 548 6076
Interests: breast cancer pathology; immunohistochemistry; prognostic and predictive factors; biomarkers

Special Issue Information

Dear Colleagues,

A major challenge in the clinical management of breast cancer is the accurate prognostication of clinical outcome and reliable prediction of which subgroups of patients will benefit (or not) from systemic treatment. Basic discoveries in cancer biology have identified key signaling pathways that drive malignant progression in breast cancer, and panels of bio-markers that assess their activation.  Recently, gene expression profiling has led to the discovery of molecular biomarker sets that define breast cancer subtypes which are associated with different prognoses and are correlated with previously identified clinical bio-markers.  In addition, distinct molecularly defined classes of tumor stroma have been associated with tumor subtypes, and have been found to enhance prognostic power. Mutational analysis and micro-RNA profiling also provide new dimensions for prognosis and prediction of treatment response. Through this special issue of Cancers dedicated towards breast cancer pathology and biomarkers, we are pleased to accept manuscripts for publication which will move us forward in our collective goal of providing optimal, personalized medical care for patients with breast cancer.

Prof. Dr. Sandip Kumar SenGupta
Guest Editor


  • breast pathology
  • immunohistochemistry
  • predictive markers
  • prognostic markers
  • breast cancer
  • personalized medicine
  • micro RNA
  • signaling pathways
  • gene expression profiling

Published Papers (2 papers)

by , , , , , ,  and
Cancers 2013, 5(1), 1-11; doi:10.3390/cancers5010001
Received: 5 November 2012; in revised form: 17 December 2012 / Accepted: 19 December 2012 / Published: 21 December 2012
Show/Hide Abstract | PDF Full-text (608 KB) | HTML Full-text | XML Full-text

by , ,  and
Cancers 2012, 4(3), 658-672; doi:10.3390/cancers4030658
Received: 6 June 2012; in revised form: 29 June 2012 / Accepted: 5 July 2012 / Published: 10 July 2012
Show/Hide Abstract | PDF Full-text (486 KB) | HTML Full-text | XML Full-text

Last update: 25 February 2014

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