Special Issue "Sleep and Brain Development"


A special issue of Brain Sciences (ISSN 2076-3425).

Deadline for manuscript submissions: closed (30 June 2013)

Special Issue Editor

Guest Editor
Dr. Marcos G. Frank
Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6060, USA
Website: http://www.med.upenn.edu/apps/faculty/index.php/g20001668/p36825
E-Mail: mgf@mail.med.upenn.edu
Phone: +215 746 0388
Fax: +215 573 9050
Interests: neural development; sleep; synaptic plasticity; glia

Special Issue Information

Dear Colleagues,

The function of sleep is an enduring biological mystery. This mystery only deepens when we look back in ontogenetic time. Across a wide a variety of animal species, sleep amounts are maximal during early development. This abundance of sleep coincides with periods of heightened brain growth and plasticity. This suggests that one function of sleep may be to promote normal brain maturation. This intuitive idea, however, has been minimally explored. A more complete understanding of sleep ontogenesis and the impact of normal and abnormal sleep on the developing brain is needed.

The current special issue will feature articles that address how sleep and sleep regulation change during development, and the interactions between sleep, brain maturation and plasticity, and behavior.

Dr. Marcos G. Frank
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 500 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.


  • ontogenesis
  • synaptic plasticity
  • sleep
  • neural development
  • infants
  • children
  • adolescence
  • fetal

Published Papers (4 papers)

by , ,  and
Brain Sci. 2014, 4(1), 150-201; doi:10.3390/brainsci4010150
Received: 27 December 2013; in revised form: 26 February 2014 / Accepted: 7 March 2014 / Published: 19 March 2014
Show/Hide Abstract | PDF Full-text (771 KB) | HTML Full-text | XML Full-text

by , ,  and
Brain Sci. 2013, 3(4), 1445-1460; doi:10.3390/brainsci3041445
Received: 4 September 2013; in revised form: 21 October 2013 / Accepted: 29 October 2013 / Published: 12 November 2013
Show/Hide Abstract | PDF Full-text (628 KB) | HTML Full-text | XML Full-text | Supplementary Files

Brain Sci. 2013, 3(2), 800-820; doi:10.3390/brainsci3020800
Received: 11 March 2013; in revised form: 15 April 2013 / Accepted: 6 May 2013 / Published: 22 May 2013
Show/Hide Abstract | PDF Full-text (2707 KB) | HTML Full-text | XML Full-text

by , , ,  and
Brain Sci. 2013, 3(1), 318-343; doi:10.3390/brainsci3010318
Received: 30 December 2012; in revised form: 30 January 2013 / Accepted: 27 February 2013 / Published: 19 March 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (3820 KB) | HTML Full-text | XML Full-text

Last update: 8 March 2013

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