Special Issue "Neurotoxicity and General Anaesthetics in the Young"
A special issue of Brain Sciences (ISSN 2076-3425).
Deadline for manuscript submissions: closed (31 January 2014)
Prof. Dr. Daqing Ma
MD, PhD, FRCA Professor of Anaesthesia and BOC Chair, Macintosh Professor, Head of Anaesthesia Research, Anaesthetics, Pain Medicine & Intensive Care, Department of Surgery & Cancer, Imperial College London, Chelsea & Westminster Hospital, 369 Fulham Road, London SW10 9NH, UK
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Interests: organoprotection (stroke, neonatal asphyxia and kidney transplant); postoperative cognitive dysfunction and Alzheimer’s disease; cancer growth and metastasis
In the early development of brain, there is an important period called the synaptogenesis period (also known as the brain growth-spurt period) which occurs in different mammalian species at different times relative to birth. In rodents, it begins a day or two before birth and ends 2 weeks after birth, whereas in humans it starts at the beginning of the third trimester and ends several years after birth. This is the critical period of neural development for establishing communications with their environment and other neurons to ensure that they develop and function appropriately; disruption at this stage by toxic agents including anaesthetic agents may compromise the normal neuronal development of the central nervous system and may cause a long term of cognitive impairment in adult stage. This special issue of BRAIN SCIENCES contains a few substantial reviews updating research advance in this area.
Prof. Dr. Daqing Ma
Manuscript Submission Information
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- developing brain
- molecular mechanism