Special Issue "Neurotoxicity and General Anaesthetics in the Young"


A special issue of Brain Sciences (ISSN 2076-3425).

Deadline for manuscript submissions: closed (31 January 2014)

Special Issue Editor

Guest Editor
Prof. Dr. Daqing Ma
Head of Anaesthesia Research, Anaesthetics, Pain Medicine & Intensive Care Department of Surgery & Cancer, Imperial College London Chelsea & Westminster Hospital, 369 Fulham Road, London SW10 9NH, UK
Website: http://www1.imperial.ac.uk/medicine/people/d.ma/
E-Mail: d.ma@imperial.ac.uk
Interests: organoprotection (stroke, neonatal asphyxia and kidney transplant); postoperative cognitive dysfunction and Alzheimer’s disease; cancer growth and metastasis

Special Issue Information

Dear Colleague

In the early development of brain, there is an important period called the synaptogenesis period (also known as the brain growth-spurt period) which occurs in different mammalian species at different times relative to birth. In rodents, it begins a day or two before birth and ends 2 weeks after birth, whereas in humans it starts at the beginning of the third trimester and ends several years after birth. This is the critical period of neural development for establishing communications with their environment and other neurons to ensure that they develop and function appropriately; disruption at this stage by toxic agents including anaesthetic agents may compromise the normal neuronal development of the central nervous system and may cause a long term of cognitive impairment in adult stage. This special issue of BRAIN SCIENCES contains a few substantial reviews updating research advance in this area.

Prof. Dr. Daqing Ma
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed Open Access quarterly journal published by MDPI.

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  • anaesthetics
  • neuroapoptosis
  • developing brain
  • molecular mechanism

Published Papers (4 papers)

Brain Sci. 2014, 4(2), 295-310; doi:10.3390/brainsci4020295
Received: 26 February 2014; in revised form: 2 April 2014 / Accepted: 5 April 2014 / Published: 16 April 2014
Show/Hide Abstract | Download PDF Full-text (226 KB) | View HTML Full-text | Download XML Full-text

Brain Sci. 2014, 4(2), 273-294; doi:10.3390/brainsci4020273
Received: 31 January 2014; in revised form: 28 March 2014 / Accepted: 31 March 2014 / Published: 16 April 2014
Show/Hide Abstract | Download PDF Full-text (399 KB)
abstract graphic

Brain Sci. 2014, 4(1), 136-149; doi:10.3390/brainsci4010136
Received: 18 December 2013; in revised form: 6 February 2014 / Accepted: 4 March 2014 / Published: 14 March 2014
Show/Hide Abstract | Download PDF Full-text (202 KB) | View HTML Full-text | Download XML Full-text

Brain Sci. 2014, 4(1), 73-90; doi:10.3390/brainsci4010073
Received: 16 December 2013; in revised form: 8 January 2014 / Accepted: 16 January 2014 / Published: 28 January 2014
Show/Hide Abstract | Download PDF Full-text (399 KB)

Last update: 14 August 2013

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