Mechanistic and Therapeutic Crosstalk across Neurodegenerative Diseases: What Can We Learn from Each Other?
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Molecular and Cellular Neuroscience".
Deadline for manuscript submissions: closed (30 September 2018) | Viewed by 13937
Special Issue Editor
2.Institute for Science and Technology in Medicine, Stoke-on-Trent, UK
3.Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK
Interests: spinal muscuspinal muscular atrophy; amyotrophic lateral sclerosis; therapeutic development; metabolism; muscle; mouse models
Special Issue Information
Dear Colleagues,
The last decade has seen tremendous advancements in uncovering novel pathological mechanisms and developing new therapeutic tools and strategies in the field of neurodegenerative diseases, which include, but are not limited to, spinal muscular atrophy, amyotrophic lateral sclerosis, multiple sclerosis, Huntington’s disease, Alzheimer’s disease, Parkinson’s disease, ataxia and spinal and bulbar muscular atrophy. While these pathologies are genetically distinct and for the most part display specific pathological hallmarks, accumulating evidence suggests that similar mechanistic perturbations can occur in two or more of these diseases and that treatment strategies developed for one disorder can have broader implications for other neurodegenerative diseases.
This Special Issue will highlight these similarities ranging from histological features, molecular pathways, tissue/cell dysfunctions, diagnostic methods, biomarkers and therapeutic developments.
Dr. Melissa BowermanGuest Editor
Manuscript Submission Information
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Keywords
- Neurodegenerative disease
- Histology
- Molecular pathway
- Diagnostic
- Biomarker
- Therapy