Special Issue "Analytical and Nanoanalytical Methods for Biomedical and Environmental Sciences 2016"

A special issue of Biosensors (ISSN 2079-6374).

Deadline for manuscript submissions: closed (30 June 2017)

Special Issue Editors

Guest Editor
Dr. Séverine Le Gac

University of Twente, Drienerlolaan 5, 7522 NB Enschede, The Netherlands
Website | E-Mail
Interests: microfluidics; miniaturized devices for medical/biological/pharmaceutical
Guest Editor
Prof. Dr. Monica Florescu

“Transilvania” University of Brasov, Faculty of Medicine, Brasov, Romania
Website | E-Mail
Interests: electrochemical and optical sensors/biosensors for medical, environmental and food applications

Special Issue Information

Dear Colleagues,

Analytical and nanoanalytical methods, which are generally used for (bio)medical and environmental science applications, comprise both labeled (fluorescence, nuclear, etc.) and label-free detection techniques, such as electrical, electrochemical, optical, piezoelectric or thermal detection. Biosensors, based on both labeled and label-free detection methods, have earned considerable interests in the recent years and they exhibit great promises for a wide range of applications in biological research, medical diagnostics, environmental analysis or even food monitoring.

For this Special Issue, “Analytical and Nanoanalytical Methods for Biomedical and Environmental Sciences 2016” we invite manuscripts dealing with biosensing for aforementioned applications above, which will be presented in the frame of the International Conference IC-ANMBES 2016 in Brasov, Romania (http://sciforum.net/conference/icanmbes), without any limitation to this. Both original research and review articles will be welcome. Original research papers should describe the development, characterization/evaluation, simulations and/or utilization of different platforms for the detection of biological active species in complex samples, with promising applications in medical diagnostics, environmental or food monitoring. Review articles should provide an up-to-date and critical state-of-the-art overview on specific biosensing techniques and/or platforms/detection mechanisms for targeted application fields. These articles can deal with microfluidics and point-of-care microdevices, optical fibers, novel material electrodes and surface functionalization strategies for the detection of specific (bio)molecules in complex samples, or they can propose new concepts and fundamental studies with potential relevance to biosensing.

Please feel free to contact us and to send us suggestions that you would like to discuss beforehand. We look forward to your contribution, and welcome your participation in this Special Issue.

Dr. Séverine Le Gac;
Dr. Monica Florescu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 350 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Biosensors
  • Microfluidics
  • Point-of-care microdevices
  • Novel materials
  • Surface functionalization

Published Papers (2 papers)

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Research

Open AccessArticle Detection of 17 β-Estradiol in Environmental Samples and for Health Care Using a Single-Use, Cost-Effective Biosensor Based on Differential Pulse Voltammetry (DPV)
Biosensors 2017, 7(2), 15; doi:10.3390/bios7020015
Received: 7 March 2017 / Revised: 24 March 2017 / Accepted: 25 March 2017 / Published: 29 March 2017
Cited by 1 | PDF Full-text (2493 KB) | HTML Full-text | XML Full-text
Abstract
Environmental estrogen pollution and estrogen effects on the female reproductive system are well recognized scientifically. Among the estrogens, 17 β-estradiol is a priority in environmental estrogen pollution, and it is also a major contributor to estrogen which regulates the female reproductive system. 17
[...] Read more.
Environmental estrogen pollution and estrogen effects on the female reproductive system are well recognized scientifically. Among the estrogens, 17 β-estradiol is a priority in environmental estrogen pollution, and it is also a major contributor to estrogen which regulates the female reproductive system. 17 β-estradiol is carcinogenic and has a tumor promotion effect relating to breast cancer, lung cancer and others. It also affects psychological well-being such as depression, fatigue and others. Thus, a simple method of detecting 17 β-estradiol will be important for both environmental estrogen pollution and health care. This study demonstrates a single-use, cost-effective 17 β-estradiol biosensor system which can be used for both environmental and health care applications. The bio-recognition mechanism is based on the influence of the redox couple, K3Fe(CN)6/K4Fe(CN)6 by the interaction between 17 β-estradiol antigen and its α-receptor (ER-α; α-estrogen antibody). The transduction mechanism is an electrochemical analytical technique, differential pulse voltammetry (DPV). The levels of 17 β-estradiol antigen studied were between 2.25 pg/mL and 2250 pg/mL; Phosphate buffered saline (PBS), tap water from the Cleveland regional water district, and simulated urine were used as the test media covering the potential application areas for 17 β-estradiol detection. An interference study by testosterone, which has a similar chemical structure and molecular weight as those of 17 β-estradiol, was carried out, and this 17 β-estradiol biosensor showed excellent specificity without any interference by similar chemicals. Full article
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Open AccessArticle A Strategy to Establish a Quality Assurance/Quality Control Plan for the Application of Biosensors for the Detection of E. coli in Water
Biosensors 2017, 7(1), 3; doi:10.3390/bios7010003
Received: 28 October 2016 / Revised: 22 December 2016 / Accepted: 27 December 2016 / Published: 3 January 2017
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Abstract
Rapid bacterial detection using biosensors is a novel approach for microbiological testing applications. Validation of such methods is an obstacle in the adoption of new bio-sensing technologies for water testing. Therefore, establishing a quality assurance and quality control (QA/QC) plan is essential to
[...] Read more.
Rapid bacterial detection using biosensors is a novel approach for microbiological testing applications. Validation of such methods is an obstacle in the adoption of new bio-sensing technologies for water testing. Therefore, establishing a quality assurance and quality control (QA/QC) plan is essential to demonstrate accuracy and reliability of the biosensor method for the detection of E. coli in drinking water samples. In this study, different reagents and assay conditions including temperatures, holding time, E. coli strains and concentrations, dissolving agents, salinity and pH effects, quality of substrates of various suppliers of 4-methylumbelliferyl glucuronide (MUG), and environmental water samples were included in the QA/QC plan and used in the assay optimization and documentation. Furthermore, the procedural QA/QC for the monitoring of drinking water samples was established to validate the performance of the biosensor platform for the detection of E. coli using a culture-based standard technique. Implementing the developed QA/QC plan, the same level of precision and accuracy was achieved using both the standard and the biosensor methods. The established procedural QA/QC for the biosensor will provide a reliable tool for a near real-time monitoring of E. coli in drinking water samples to both industry and regulatory authorities. Full article
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