Special Issue "Non-coding RNA"
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: closed (31 December 2012)
Prof. Dr. Ling-Ling Chen
Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue-yang Road, Shanghai 200031, China
Phone: +86 21 5492 0000
Fax: +86 21 5492 1011
Interests: noncoding RNAs; RNA editing; gene expression regulation; stem cell biology
Dr. Yuntao (Steve) Mao
Department of Chemistry and Chemical Biology, Harvard University 12 Oxford St, Cambridge, MA 02138, USA
Phone: +1 617 496-8654
Interests: noncoding RNAs; mammalian nuclear organization; single-cell sequencing; cancer biology
RNA has long been known to connect genes and proteins through gene transcription and protein translation. Recently, small noncoding RNAs, such as siRNAs, microRNAs, and piRNAs, have been demonstrated to play important roles in many aspects of gene regulation. New classes of noncoding RNAs, long noncoding RNAs in particular, have lately been identified and functionally characterized. The centrality of RNA in fundamental cellular processes is now highly appreciated. This issue intends to glance the recent history of noncoding RNAs and to showcase their regulatory roles in gene expression at multiple levels. Therefore, we invite submission of high quality review manuscripts that cover any aspect of the biochemistry, biophysics, cell biology, genetics, physiology, disease, and evolution of both small and long noncoding RNAs, viral and bacterial RNAs, and other regulatory RNAs.
We look forward to your contributions.
Prof. Dr. Ling-Ling Chen
Dr. Yuntao (Steve) Mao
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 300 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- noncoding RNAs
- gene expression regulation
Biomolecules 2012, 2(4), 608-621; doi:10.3390/biom2040608
Received: 26 October 2012; in revised form: 19 November 2012 / Accepted: 23 November 2012 / Published: 4 December 2012| Download PDF Full-text (577 KB) | Download XML Full-text
Biomolecules 2013, 3(1), 157-167; doi:10.3390/biom3010157
Received: 14 January 2013; in revised form: 1 February 2013 / Accepted: 3 February 2013 / Published: 11 February 2013| Download PDF Full-text (152 KB)
Review: Panning for Long Noncoding RNAs
Biomolecules 2013, 3(1), 226-241; doi:10.3390/biom3010226
Received: 18 December 2012; in revised form: 21 February 2013 / Accepted: 21 February 2013 / Published: 28 February 2013| Download PDF Full-text (365 KB) | Download XML Full-text
Biomolecules 2013, 3(2), 287-302; doi:10.3390/biom3020287
Received: 2 March 2013; in revised form: 22 March 2013 / Accepted: 27 March 2013 / Published: 9 April 2013| Download PDF Full-text (235 KB) | Download XML Full-text
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Type of Paper: Review
Title: Tumor protein p63/microRNA regulatory circuitry in cancer cells
Author: Edward A. Ratovitski
Affiliation: Head and Neck Cancer Division and Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; E-Mail: firstname.lastname@example.org
Abstract: MicroRNAs are involved in multiple regulatory mechanisms underlying response of cancer cells to stress leading to apoptosis, cell cycle arrest and autophagy. Many molecular layers are implicated in such cellular response including epigenetic regulation of transcription, RNA processing, metabolism, signaling. The molecular circuitry between tumor protein (TP) p53 family members and specific microRNAs is a key functional network supporting tumor cell response to chemotherapy playing a decisive role in chemosensitivity or chemoresistance of human epithelial cancers. TP63 was shown to modulate the expression of numerous microRNAs in squamous cell carcinoma cells exposed to cisplatin leading to reduction or induction of specific microRNA targets involved in cell cycle arrest, apoptosis, autophagy, metabolism and epigenetic transcriptional regulation, thereby providing the groundwork for novel chemotherapeutic venues.
Last update: 23 May 2013