Special Issue "Immune Mechanisms in Fish"
A special issue of Biology (ISSN 2079-7737).
Deadline for manuscript submissions: 15 May 2015
Prof. Dr. Brian Dixon
Department of Biology, University of Waterloo, ESC 350, 200 University Ave. W, Waterloo, Ontario, N2L 3G1, Canada
Fish immunity studies are at a pivotal point. Genomes of zebrafish and fugu have been examined in detail, those of rainbow trout, cod and coelacanths have recently been released, allowing for comparative studies revealing key evolutionary differences, such as lobe-finned fishes more closely resembling tetrapods or the lack of major histocompatibility class II and associated accessory genes in cod. In addition, novel technologies such as RNAseq have permitted large scale views of gene regulation. Functional studies in fish have provided novel regulatory and effector mechanisms that, upon subsequent study, are also present in mammals, such as transferrin activation of macrophages and phagocytic B cells. With this basis, future functional studies will provide even deeper insights into both mechanisms of fish immunity and the evolution of immune systems. For this special issue, we will review the state of the art in key areas of fish immunity as a basis for future studies.
Prof. Dr. Brian Dixon
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 600 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- comparative immunology
- innate immunity
- adaptive immunity
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Phagocytosis in teleost. Implications of the new cells involved
Author: María Ángeles Esteban
Affiliation: Department of Cell Biology and Histology, Faculty of Biology, University of Murcia. 30100 Murcia, Spain; E-Mail: email@example.com
Abstract: Phagocytosis is the process by which certain cells engulf some solid particles to form internal vesicles known as phagosomes. Phagocytosis is in fact a specific form of endocytosis involving the vesicular interiorization of particles. In higher animals phagocytosis is essentially a defensive reaction against infection and invasion of the body by foreign substances and, in the immune system, phagocytosis is a major mechanism used to remove pathogens and/or cell debris. For these reasons, phagocytosis in vertebrates has been recognized as a critical component of the innate and adaptive immune responses to pathogens. Furthermore, more recent studies have revealed that phagocytosis is also crucial for tissue homeostasis and remodeling. Professional phagocytes in teleosts are monocyte/macrophages and granulocytes. Nevertheless, in recent years phagocytic properties have also been attribute to teleost lymphocytes and thrombocytes. The possible implications of such cells on this important biological process will be considered and discussed.
Last update: 5 January 2015