Dear Colleagues,

Biofilms represent a microbial catalyst format, which, in principle, exhibits an infinite turn-over number (TN) due to the fact that they are constituted of naturally immobilized cells continuously regenerating themselves. Their natural, intrinsic ability of tolerating different kind of stresses, natural (desiccation, starvation, predators) or process related (toxic compounds, pH shifts, high salt) make biofilms an ideal system for continuous bioprocess development.

However, although widely accepted as a potent alternative to planktonically growing cell cultures, there are still a number of challenges to be addressed. Developing novel reactor concepts, technical solutions for mass transfer limitations, highly diluted bleed streams and low specific activities are as important as designing novel biofilm catalysts and understanding biofilm regulation and development.

Additionally, new developments as multispecies biofilms, multistep catalysis and activities in the bio electrochemical field are highly exciting and open up new areas in biofilm research.

In this Special Issue we would like to give an overview of the latest advances in the field of product driven biofilm research, spanning the area of basic to applied biofilm studies. We look forward to receiving your contributions to these cutting edge issues.

Prof. Dr. Katja Buehler
Guest Editor

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• Biocatalysis
• Continuous bioprocess
• Biofilm reactors
• Biofilm reaction concepts
• Multi-species biofilms
• Genetic engineering
• Biofilm regulation (C-di-GMP/RpoS)
• Modelling