Special Issue "Oxidative Stress and Neurodegenerative Diseases"


A special issue of Antioxidants (ISSN 2076-3921).

Deadline for manuscript submissions: 30 September 2014

Special Issue Editor

Guest Editor
Dr. Wenlan Liu
Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico, MSC09 5360, Albuquerque, NM 87131-0001, USA
E-Mail: WeLiu@salud.unm.edu
Phone: +505 272 2580
Fax: +505 272 0704
Interests: ischemic brain injury; neurodegenerative diseases; aging; oxidative stress; cell signaling pathways

Special Issue Information

Dear Colleagues,

Imbalance between generation and elimination of free radicals leads to oxidative stress and free radicals mediated tissue injury. Many lines of evidence suggest that oxidative stress plays an important role in neuronal loss in several CNS degenerative disorders, such as Alzheimer’s disease, Parkinson’s disease, ischemic stroke, aging, and amyotrophic lateral sclerosis. Mitochondrial oxidative metabolism, NADPH oxidase, nitric oxide synthase, and phospholipids metabolism are potential sources of intracellular free radicals. It is well known that overproduction of free radicals produces damage to lipids, proteins and DNA and induces neuronal apoptosis or necrosis, however much work is needed to clarify the mechanisms by which excessive free radicals are generated in the diseased brain and the molecular mechanisms by which free radicals induce neuronal death. This Issue will allow publication of all aspects regarding oxidative stress and neurodegenerative diseases and of therapeutic strategies targeting free radical generation.

Prof. Dr. Wenlan Liu
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.


  • free radicals
  • oxidative stress
  • neurodegeneration
  • antioxidants

Published Papers (2 papers)

by , , ,  and
Antioxidants 2014, 3(2), 245-277; doi:10.3390/antiox3020245
Received: 8 February 2014; in revised form: 9 March 2014 / Accepted: 17 March 2014 / Published: 10 April 2014
Show/Hide Abstract | PDF Full-text (564 KB) | HTML Full-text | XML Full-text
abstract graphic

by , , , , ,  and
Antioxidants 2014, 3(2), 200-211; doi:10.3390/antiox3020200
Received: 26 December 2013; in revised form: 10 March 2014 / Accepted: 17 March 2014 / Published: 2 April 2014
Show/Hide Abstract | PDF Full-text (337 KB) | HTML Full-text | XML Full-text

Last update: 28 May 2014

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