Modern Methods in Antibody Expression and Purification

A special issue of Antibodies (ISSN 2073-4468).

Deadline for manuscript submissions: closed (28 February 2019) | Viewed by 178

Special Issue Editor

Merck Research Labs, 33 Avenue Louis Pasteur, Boston, MA 02115, USA
Interests: antibody discovery; therapeutic antibody; protein engineering

Special Issue Information

Dear Colleagues,

Antibody purification is an essential technique for most drug discovery programs in addition to many academic research projects. This Special Issue will cover the basic principles of monoclonal antibody (mAb) generation from multiple expression systems including mammalian cells and yeast. It will focus on strategies for increasing throughput at various scales, which is often critical during therapeutic antibody campaigns. The Special Issue will also describe techniques to purify modified antibody formats such as bispecific antibodies, monovalent Fc-fusions, and conjugates which often require several polishing steps. Additionally, the Special Issue will address the preparation of samples for in vivo experiments, such as novel endotoxin removal strategies.

Dr. Brian Hall
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibodies is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Antibody
  • mAb
  • purification
  • expression
  • Fc-fusion
  • Bispecific
  • ADC

Published Papers

There is no accepted submissions to this special issue at this moment.
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