Special Issue "Biofilm Infection"
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: closed (30 April 2014)
Prof. Dr. Gordon Ramage
Infection and Immunity Research Group, Glasgow Dental School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, 378 Sauchiehall Street, Glasgow, G2 3JZ, UK
Interests: biofilms; candida; aspergillus; oral; respiratory; biomaterial; resistance; antibiotic; antifungals; naturals
Dr. Karen Smith
Institute for Healthcare Associated Infections, University of the West of Scotland, Ayr, UK
Interests: resistance; chronic biofilm infections; novel antimicrobials; wounds; respiratory tract
In clinical microbiology when chemotherapeutic management fails, there is a tendency to focus on defined antimicrobial resistance mechanisms related to inheritable genetic traits. However, it is increasingly apparent that treatment failure may be related to microbial biofilms, which are an increasingly important clinical problem. Microbial biofilms are complex and heterogeneous structures encased within extrapolymeric matrix, and cells encased within, exhibit dramatic change in their resistance profiles compared to free-floating counterparts by adapting to their environment and changing their phenotypic and genotypic characteristics accordingly.
While our understanding of the basic biology of microbial biofilms has greatly improved, we still face challenges in developing effective clinical management strategies. Some key areas still require exploration:
- How do we diagnose biofilm related infections more effectively?
- What is the impact of biofilms on clinical outcomes?
- How do we manage polymicrobial biofilm infection?
- Are there methods to augment existing chemotherapeutic strategies?
- Does sub-optimal treatment of biofilms make them more pathogenic?
"Antibiotics" will publish a special issue focusing on the clinical management of biofilm related infections. It is our pleasure to invite submissions of high quality research based papers related to the questions mentioned above.
Prof. Dr. Gordon Ramage
Dr. Karen Smith
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 300 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
Article: A Novel Organo-Selenium Bandage that Inhibits Biofilm Development in a Wound by Gram-Positive and Gram-Negative Wound Pathogens
Antibiotics 2014, 3(3), 435-449; doi:10.3390/antibiotics3030435
Received: 30 April 2014; in revised form: 7 August 2014 / Accepted: 19 August 2014 / Published: 25 August 2014| PDF Full-text (1807 KB) | HTML Full-text | XML Full-text
Review: Foreign Body Infection Models to Study Host-Pathogen Response and Antimicrobial Tolerance of Bacterial Biofilm
Antibiotics 2014, 3(3), 378-397; doi:10.3390/antibiotics3030378
Received: 2 April 2014; in revised form: 1 July 2014 / Accepted: 6 August 2014 / Published: 21 August 2014| PDF Full-text (1139 KB)
Concept Paper: Bacteriophages and Biofilms
Antibiotics 2014, 3(3), 270-284; doi:10.3390/antibiotics3030270
Received: 25 April 2014; in revised form: 6 June 2014 / Accepted: 10 June 2014 / Published: 25 June 2014| PDF Full-text (851 KB) | HTML Full-text | XML Full-text
Last update: 25 November 2013