Mammalian DNA Repair
2015-02-07 to 2015-02-08
The focus of this meeting is to empower the young scientists by providing them with a framework for informal and fertile discussions among peers on their most recent research findings as well as on career paths. Scientific presentations will be at the forefront of research on mechanisms of DNA repair, cytoplasmic and nuclear DNA damage signaling and consequences on cell fate, while a career panel will bring together scientists from different backgrounds such as academia, industry, publishing/editing and entrepreneurship to share their insight regarding career development.
Structural Dynamics in Cellular Communication
2015-02-09 to 2015-02-10
The conference will cover the latest advances in protein science, focusing on systems structural biology, the functional role of structural dynamics, the organization of complexes and key technological advances. During four plenary sessions this first edition will handle the following topics: macromolecular machines and assemblages; protein network dynamics; protein fluctuations and function; and membrane proteins and complexes.
Genomic Instability and DNA Repair
2015-03-01 to 2015-03-06
Whistler Conference Centre, Whistler, British Columbia, Canada
Far from being a single process, genome maintenance involves the integration of multiple DNA damage repair and signaling pathways that are deeply influenced by cell cycle progression, chromatin composition, gene transcription, genome organization and the differentiation state of the cell. Preservation of genomic integrity is of paramount importance for cellular homeostasis, organismal development and tumor suppression. Accordingly, defects in the pathways that signal and repair DNA damage cause pathologies that include cancer, neurological disorders, premature aging and immunodeficiency. Our understanding of genome maintenance in the context of the multitude of intracellular transactions remains woefully incomplete and topic sessions addressing this issue will comprise a major theme of the conference. The program uniquely connects fields that otherwise rarely meet on a single occasion and will cover genome stability, development, disease, telomere biology and stem cell function. The meeting will highlight the latest trends including how genomic technologies have revolutionized our view of genome integrity and led to the discovery of new types of genome rearrangements whose mechanistic underpinnings remain largely unknown. The unusually broad scope of the conference will bring together scientists operating at the leading edge of multiple disciplines ranging from basic cell biology to pre-clinical oncology. Interactions between junior and seasoned investigators, as well as interdisciplinary contacts, will be fostered through poster presentations, workshops and plenary sessions, some of which are shared with the concurrent Keystone Symposia meeting on DNA Replication and Recombination, which will focus on the highly complementary theme of repair in the setting of DNA replication.
2015-03-08 to 2015-03-13
Lucca (Barga), Italy
The 2015 Gordon Research Conference on RNA Editing brings together researchers at the forefront of the field of editing and modification of nucleic acids. The impact of RNA and DNA editing and modification on biological systems is well-documented and progress in high-throughput nucleic acid sequencing techniques has clearly demonstrated that the information encoded in genomes is extensively altered at the level of gene expression. These changes impact processes as diverse as gene expression, protein synthesis, RNA splicing, somatic hypermutation, viral replication, organismal development, and immunoglobulin class switch recombination and are demonstrated to affect numerous human diseases, including cancer, metabolic disorders, pathogen recognition, immune system disorders, mitochondrial diseases, and viral and parasite pathogenesis. This biennial conference series has been held every other year since 1997, and is the only international meeting devoted to bringing together researchers working on the biogenesis, detection, and physiological consequences of normal and pathologic RNA-editing and modification events. The GRC provides a forum for researchers from diverse fields to interact extensively in an environment that promotes active discussion. Presentations from scientists at the frontiers of the field and at all stages of their careers will continue to enrich the highly collaborative nature of the RNA and DNA editing and modification fields and will excite new ideas and collaborations from among meeting participants leading to a broader understanding of these important processes in biology.
Long Noncoding RNAs: From Evolution to Function
2015-03-15 to 2015-03-20
Keystone Resort, Keystone, Colorado, USA
It has become clear that metazoan genomes are replete with transcription from non-protein-coding regions, generating many long non-coding RNA (lncRNA) transcripts. Recent progress has enabled genome-wide mapping of lncRNAs and has unraveled unifying themes; lncRNAs function as epigenetic regulators, scaffolds, decoys, and enhancers. While these and other themes have been pursued in several meetings, the field has matured in numerous novel directions, and we will leverage these to comprehensively characterize lncRNAs across metazoan genomes. We aim to broaden our horizons with emerging data from humans and model systems, empowered by novel genomic technologies, including RNA-protein interaction mapping (CLIP- and RIP-seq), reverse genetics for lncRNAs not conserved in evolution (RNA sequencing in control and lncRNA-perturbed backgrounds), and proteogenomics to empirically bound the translational output of putative lncRNAomes. These topics have recently amassed diverse insights into RNA biology. The goal of our meeting is to integrate novel findings, enhance previously proposed models of lncRNA function, and generate new testable hypotheses. Our synthesis of RNA structure, function, evolution, and informatics will foster progress in this rapidly growing field.
2015 annual meeting of the American Society of Biochemistry and Molecular Biology
2015-03-28 to 2015-04-01
Boston Convention & Exhibition Center, 415 Summer St, Boston, MA 02210
The 14 themes
of the meeting symposia cover the broad range of biomolecules and systems that interest the ASBMB membership. We are certain that you will find new twists in the recent discoveries as well as new areas in which the science is advancing rapidly.
10th EFMC Short Course on Medicinal Chemistry Small-Molecule Modulation of Protein-Protein Interactions (PPIs)
2015-04-12 to 2015-04-15
The Crossroads of Lipid Metabolism and Diabetes
2015-04-19 to 2015-04-24
Tivoli Hotel and Congress Center, Copenhagen, Denmark
The prevalence of obesity and Type 2 diabetes are reaching epidemic proportions throughout the world. One of the key features of these insulin-resistant disorders is disturbances in lipid metabolism. Overproduction of fatty acids in the liver leads to hypertriglyceridemia and low HDL cholesterol, which are important risk factors for the development of atherosclerosis, the most common cause of death among diabetic patients. In addition, excess fatty acid production and the accumulation of hepatic cholesterol promote the development of non-alcoholic steatohepatitis (NASH), which has become one of the leading indications for liver transplantation. In addition, disturbances in bile acid metabolism may also contribute to the development of atherosclerosis, as well as gallstones. The goal of this meeting is to provide attendees with the latest advances in the understanding of mechanisms governing the metabolism of lipids and how these pathways become dysregulated in the insulin resistant state. Elucidation of mechanisms underlying lipid metabolism may reveal new therapeutic strategies to combat atherosclerosis and other complications of diabetic patients. This program will stimulate interactions that are likely to augment and accelerate this process.
ICBMB 2015 International Conference on Biochemistry and Molecular Biology
2015-04-22 to 2015-04-23
The aim of the conference is to promote research in the field of Biochemistry and Molecular Biology. Another goal is to facilitate exchange of new ideas in these fields and to create a dialogue between scientists and practitioners.
Telomeres & Telomerase
2015-04-28 to 2015-05-02
We are pleased to offer the ninth Cold Spring Harbor meeting on Telomeres & Telomerase
to bring together a diverse group of scientists studying various molecular, cellular and genetic aspects of telomeres and telomerase biology. The meeting will begin at 7:30 pm on Tuesday, April 28, and run through lunch on Saturday, May 2, 2015. The meeting is intended to provide a format for the exchange of ideas and information, to discuss the latest research findings and technical advances, and to facilitate interaction amongst groups active in diverse systems.
Non-Coding RNA: New Mechanisms and Approaches
2015-05-18 to 2015-05-19
Emerging new roles of non-coding RNA are transforming biology. Leaders in the field will report on advances in our understanding of RNA in genome stability, immunology, epigenetic inheritance. This meeting will cover a range of systems including protists, invertebrates and mammals. A major focus will be how to translate new RNA mechanisms into new therapeutic approaches.
RNA 2015, The Twentieth Annual Meeting of the RNA Society
2015-05-26 to 2015-05-31
Madison Wisconsin, USA
This meeting will discuss the pathways, by which RNA molecules exert control over all levels of gene expression in amoebae, with special emphasis to the processes in the model organism Dictyostelium discoideum
The 2015 IMB Conference DNA repair and genome stability within chromatin environments
2015-06-04 to 2015-06-07
MicroRNAs and Noncoding RNAs in Cancer
2015-06-07 to 2015-06-12
Keystone Resort, Keystone, Colorado, USA
MicroRNAs and other noncoding RNAs have recently emerged as key regulators of gene expression during development and are frequently mis-expressed in human disease states, in particular cancer. MicroRNAs act to promote or repress cell proliferation, migration and apoptosis during development, all processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. Their small size and molecular properties make microRNAs amenable as targets and therapeutics in cancer treatment. MicroRNAs thus present a paradigm shift in thinking about gene regulation during development and disease and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer. However, while hundreds of human microRNAs and noncoding RNAs are known, relatively little is known about their roles and targets, and there is still a limited literature on using these molecules in the clinic. The specific aims of this meeting serve to address these deficiencies and are as follows: 1) Focus on the exciting biology of microRNAs and noncoding RNAs in controlling developmental and cancer processes like cell proliferation, differentiation, cell cycle, apoptosis and metastasis. This meeting will highlight the best current research into the role that miRNAs play in these fundamental processes and provide the basic understanding that will drive the invention of powerful clinical tools; 2) Focus on the latest efforts to harness the power of these RNAs as agents in the fight against cancer. Discussions will range from use of miRNAs as diagnostic and prognostic markers in cancer, to SNPs providing risk factors for cancer, to the delivery and effectiveness of small RNA therapeutics in clinically relevant settings; 3) Attract the best researchers working in small RNAs and cancer to one place for critical discussions that will advance the field and accelerate the benchside to bedside use of this technology; and 4) Provide a stimulating environment where students, postdocs and junior investigators can present and discuss their research with the best minds in the field.
4th Beilstein Glyco-Bioinformatics Symposium
2015-06-22 to 2015-06-26
International Conference on Transcriptomics
2015-07-27 to 2015-07-29
Orlando, FL, USA
We welcome you to the International Conference on Transcriptomics
popularly known as Transcriptomics-2015, which is going to be held during July 27-29, 2015 at Hotel Hyatt Regency - Orlando International Airport, Florida, USA. The theme of the conference "Transcriptome Analysis: Unveiling the layers of Expression
" is all about simplifying the complex phenomenon behind protein expression by RNA-Seq. Transcriptomics
is a cross-disciplinary area concerned with transcriptome analysis
and how the next generation sequencing
is replacing microarrays as the choice method to accurate expression profiling
and quantify overall gene expression level. Transcriptomics research provides a profitable business opportunity to several pharmaceutical and biotech companies as these technologies have wide application areas such as drug discovery and research followed by clinical diagnosis of various disorders. With the arrival of advanced technological platforms, it creates a need for effective bioinformatics tools and services in order to manage and analyze huge amount of data released from these technologies. Transcriptomics mainly focusses on the Universities, Institutes and major Societies along with big market in Transcriptome technology.
Metabolic Signaling & Disease: From Cell to Organism
2015-08-11 to 2015-08-15
Metabolic regulation is at the intersection of many scientific fields, ranging from basic biochemistry and molecular biology to physiology, to the study of disease pathogenesis. Currently, a major challenge for these diverse fields is to define commonalities and differences in metabolic pathways and their regulation, and determine the role of these processes for physiology and disease states. This meeting will fill an important gap by bringing together outstanding researchers focused on diverse pathways, cell types, or diseases with a common theme of understanding how metabolism is regulated in physiology and disease states.
Eukaryotic mRNA Processing
2015-08-18 to 2015-08-22
We are pleased to host the tenth Cold Spring Harbor meeting on Eukaryotic mRNA Processing, which will begin at 7:30 pm on Tuesday, August 18 and run through lunch on Saturday, August 22, 2015. The meeting will focus on the mechanisms and regulation of mRNA splicing, polyadenylation, turnover, localization and RNA interference. It will include all aspects mRNA transport, processing and control, including microRNA function. The meeting is intended to provide a format for the exchange of ideas and information, to discuss the latest research findings and technical advances, and to facilitate interaction amongst groups active in diverse systems.
Signalling 2015: Cellular Functions of Phosphoinositides and Inositol Phosphates
2015-09-01 to 2015-09-04
Robinson College, Cambridge, UK
78th Harden Conference: Protein Kinases in Health and Disease
2015-09-15 to 2015-09-18
Norton Park Hotel, Winchester, UK
The aim of this meeting is to highlight new research on the regulation and function of protein kinases in cancer, inflammation and metabolism. Speakers from the pharmaceutical sector will give an update on progress in the development and therapeutic use of specific kinase inhibitors. The regulation of kinase activation by ubiquitination, and the possibility of therapeutic targeting this post-translational modification will also be discussed. In addition, there will be a session focusing on methodological advances in kinase research.
PI3K-like protein kinases
2015-11-03 to 2015-11-05