During the last two decades the Central Dogma of Biology, which states that genetic information flows from DNA into messenger RNAs (mRNAs) via transcription, and from mRNAs into functional proteins via translation, has been shown to be far more complicated than what had long been accepted. Indeed, cells transcribe thousands of RNAs, which neither encode proteins nor have a structural function (like tRNAs or rRNAs), but which nonetheless play essential roles in the regulation of gene expression. These RNAs, which are collectively referred to as non-coding RNAs (ncRNAs), vary greatly in their size (twenty to several thousand nucleotides), in their biosynthetic pathway and in their modus operandi. Found in virtually all organisms, ncRNAs, which coordinate the expression, stability and/or inheritance of genes either at the transcriptional or at the posttranscriptional level, continue to be an intense and exciting area of research. Continue reading →
Glycoproteins are formed through protein glycosylation, the post-translational addition and processing of covalently bound oligosaccharide chains. Variations in the glycoform of proteins result from multiple factors in this process, such as enzyme and substrate availability, and these differences can influence the stability and biological function of the protein. Continue reading →
In 2012 International Journal of Molecular Sciences started to award an annual price to recognize outstanding papers related to chemistry, molecular physics and molecular biology that meet the high standards of this journal. We are pleased to announce the third “IJMS Best Paper Award” for 2014. Nominations were made by the Section Editors-in-Chief of IJMS from all papers published in 2010.
1st prize: Parul Vatsa, Lisa Sanchez, Christophe Clement, Fabienne Baillieul and Stephan Dorey
Rhamnolipid Biosurfactants as New Players in Animal and Plant Defense against Microbes
2nd prize: Junko Okuda-Shimazaki, Saiko Takaku, Koki Kanehira, Shuji Sonezaki and Akiyohshi Taniguchi
Effects of Titanium Dioxide Nanoparticle Aggregate Size on Gene Expression
3rd prize: Giuseppe Calogero, Gaetano Di Marco, Silvia Cazzanti, Stefano Caramori, Roberto Argazzi, Aldo Di Carlo and Carlo Alberto Bignozzi
Efficient Dye-Sensitized Solar Cells Using Red Turnip and Purple Wild Sicilian Prickly Pear Fruits
1st prize: Kati Hanhineva, Riitta Törrönen, Isabel Bondia-Pons, Jenna Pekkinen, Marjukka Kolehmainen, Hannu Mykkänen and Kaisa Poutanen
Impact of Dietary Polyphenols on Carbohydrate Metabolism
1st prize: Sonia De Pascual-Teresa, Diego A. Moreno and Cristina García-Viguera
Flavanols and Anthocyanins in Cardiovascular Health: A Review of Current Evidence
For more details, please refer to the IJMS Best Paper Award 2014 Editorial.
Earlier Editions of the Award