Special Issue "Fungal Metabolites"
A special issue of Agriculture (ISSN 2077-0472).
Deadline for manuscript submissions: closed (30 June 2016)
Dr. Anna Andolfi
Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte S. Angelo Via Cintia 4, I-80126 Naples, Italy
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Phone: +39 081 2539179
Interests: secondary metabolites in plant-pathogen interaction; natural substances with biological activity; chromatographic techniques, spectroscopic methods
Dr. Rosario Nicoletti
With an estimated number of about 1.5 milion species, fungi are among the most widespread organisms on Earth. They are known to be able to adapt to almost all ecological niches in any environment, where they play many different roles as saprophytes, pathogens, predators, parasites, hosts, and/or symbionts.
Such an adaptability is reflected by their capacity to produce a wide array of secondary metabolites. Mycotoxins, phytotoxins, plant growth regulators, antibiotics, insecticides, enzyme inhibitors, etc., are not essential for the survival of the producing organism, but exert a fundamental role for its development. Thus far, the ecological significance and the biological effects of the majority of such compounds have not been adequately elucidated. Moreover, gradual global warming is modifying the geographical distribution of many species, with possible, ensuing, and significant modifications in their metabolic profiles.
The great interest of the scientific community in these compounds derives from the opportunity to identify products to be used in human medicine, in agriculture, and in industry, such as drugs, pesticides, and raw materials. The very large progress made in the field of mycology, genetics, and organic and analytical chemistry have enabled researchers to use more sophisticated techniques for culturing fungi, for their taxonomic identification, for biological assays, for the isolation, structural and stereo-structural characterization of novel bioactive metabolites, and for their rapid detection in vitro and in vivo. Further implications are often derived in view of resorting to synthetic methods for mass production of the active target molecules.
This Special Issue is destined to gather reviews and original experimental papers on all the above-reported aspects, in the expectation that it may serve as a boost for a further development of knowledge in this fascinating and continuously evolving research field.
Dr. Anna Andolfi
Dr. Rosario Nicoletti
Manuscript Submission Information
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- fungal secondary metabolites
- bioactive compounds
- structure elucidation