Next Article in Journal
Optimized Use of Sensors to Detect Critical Full Load Instability in Large Hydraulic Turbines
Previous Article in Journal
Health Monitoring of Composite Structures via MEMS Sensor Networks: Numerical and Experimental Results
Article Menu

Article Versions

Export Article

Open AccessAbstract
Proceedings 2017, 1(8), 760; doi:10.3390/proceedings1080760

Redox Cycling Realized in Paper-Based Electrochemical Biosensor for Highly-Selective Detection of Potassium Ferrocyanide in the Presence of Ascorbic Acid

Department of Electrical and Electronic Engineering, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan
Presented at the 5th International Symposium on Sensor Science (I3S 2017), Barcelona, Spain, 27–29 September 2017.
*
Authors to whom correspondence should be addressed.
Published: 4 December 2017
(This article belongs to the Proceedings of the 5th International Symposium on Sensor Science (I3S 2017))
Download PDF [153 KB, uploaded 4 December 2017]

Abstract

Redox cycling is a phenomenon that occurs for redox species due to close interelectrode distance. Two electrodes, the generator electrode (GE) and the collector electrode (CE), can detect steady-state current which are oxidation and reduction current when those are held at oxidation and reduction potential. Using redox cycling, redox species such as dopamine can be measured in the presence of interfering irreversible species [1–3]. However, redox cycling needs expensive micro-fabrication process for electrode arrangement. In this work, we show detection of potassium ferrocyanide (Ferro) in the presence of ascorbic acid under redox cycling condition using paper-based biochemical sensor (PBBS). PBBS has a feature which defines the interelectrode distance by the thickness of paper (180 µm) without any micro-fabrication process [4]. To define the interelesctrode distance, we sandwiched chromatography paper (ChrPr) between two gold plates (5 mm × 10 mm) acting as GE and CE. Mixed solutions were prepared by adding Ferro (0, 1, 3, 6, 10 mM) to phosphate buffered saline (PBS) in the presence or absence of 10 mM L(+)-Ascorbic Acid Sodium Solt (L-AAS). Ferro and L-AAS are known as reversible and irreversible species, respectively. Measurements of each solution were performed through chronoamperometry (CA) technique by applying constant oxidation potential (+500 mV) and reduction potential (−200 mV) to GE and CE, respectively. As a result, we obtained the reduction current from Ferro, not from L-AAS. These results indicated that the electrochemical current flowing through CE were due to electron transfer to the redox species. Steady-state current of mixtures obtained in CE were in agreement with the result of Ferro solution. Thus, these experimental results indicate that our sensor can selectively detect reversible redox species by excluding the interfering irreversible species. This study suggests potential applications such as the measurement of dopamine.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Yamamoto, S.; Uno, S. Redox Cycling Realized in Paper-Based Electrochemical Biosensor for Highly-Selective Detection of Potassium Ferrocyanide in the Presence of Ascorbic Acid. Proceedings 2017, 1, 760.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Proceedings EISSN 2504-3900 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top