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Proceedings 2017, 1(4), 537; doi:10.3390/proceedings1040537

Integration and Bio-Functionalization of Vertically Aligned Carbon Nanotube Forests on High Frequency AlN Gravimetric Sensors

1
GMME-CEMDATIC, ETSI de Telecomunicación, Universidad Politécnica de Madrid, 28040 Madrid, Spain
2
Confocal Microscopy Unit, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain
Presented at the Eurosensors 2017 Conference, Paris, France, 3–6 September 2017.
*
Author to whom correspondence should be addressed.
Published: 7 August 2017
Download PDF [759 KB, uploaded 4 September 2017]

Abstract

In this work, we grow different types of carbon nanotube (CNT) forests directly on AlN-based electroacoustic biosensors and study their functionalization efficiency. CNTs are used to increase the effective surface area of the sensor, pursuing a better sensitivity, without increasing the sensor capacitance. Here we use a general method for CNT bio-functionalization with specific receptors for targeted species. First, we make them hydrophilic. Next, we cover them with alternating polymers. Finally, we incubate their surface in an N-hydroxysuccinimide biotin solution. To study the functionalization homogeneity along the CNT length, Streptavidin conjugated with fluorescein isothiocyanate is used as the targeted species for confocal fluorescence microscopy characterization.
Keywords: AlN electroacoustic resonators; carbon nanotube forest integration; bio-functionalization; gravimetric bio-sensors AlN electroacoustic resonators; carbon nanotube forest integration; bio-functionalization; gravimetric bio-sensors
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Escolano, J.M.; Marco, B.; Mirea, T.; Olivares, J.; Clement, M.; Megias, D.; Iborra, E. Integration and Bio-Functionalization of Vertically Aligned Carbon Nanotube Forests on High Frequency AlN Gravimetric Sensors. Proceedings 2017, 1, 537.

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