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Proceedings 2017, 1(4), 510; doi:10.3390/proceedings1040510

Sensor Array Based on Molecularly Imprinted Polymers for Simultaneous Detection of Lipoproteins

1
Department of Physical Chemistry, Faculty for Chemistry, University of Vienna, 1090 Vienna, Austria
2
Department of Medical Technology, Faculty of Allied Health Sciences, Burapha University, Chonburi 20131, Thailand
3
Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla 90112, Thailand
Presented at the Eurosensors 2017 Conference, Paris, France, 3–6 September 2017.
*
Author to whom correspondence should be addressed.
Published: 8 August 2017
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Abstract

Herein we report a sensor array based on quartz crystal microbalance (QCM) to simultaneously detect two biomarkers, namely low-density lipoprotein (LDL), and high-density lipoprotein (HDL). Selective recognition takes place through molecularly imprinted polymers (MIP) with both MIPs and corresponding non-imprinted polymer (NIP) as reference electrode. Sensor array performs highly appreciably in term of selectivity to LDL and HDL (defined through its cholesterol LDL-C, and HDL-C) when operated in 10 mM PBS. The sensor response time is less than 15 min. Furthermore, coefficients of variation indicating precision of our sensor array are at 2%–8%.
Keywords: lipoproteins sensor array; low-density lipoprotein; high-density lipoprotein; molecularly imprinted polymer; quartz crystal microbalance lipoproteins sensor array; low-density lipoprotein; high-density lipoprotein; molecularly imprinted polymer; quartz crystal microbalance
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Chunta, S.; Singsanan, S.; Suedee, R.; Lieberzeit, P.A. Sensor Array Based on Molecularly Imprinted Polymers for Simultaneous Detection of Lipoproteins. Proceedings 2017, 1, 510.

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