Next Article in Journal
H2-Sensing Performance of 2D WO3 Nanostructure—Effect of Anodization Parameter
Previous Article in Journal
Ionogel—Based Composite Material for CO2 Sensing Deposited on a Chemiresistive Transducer
Article Menu
Issue 4 (September) cover image

Article Versions

Export Article

Open AccessProceedings
Proceedings 2017, 1(4), 304; doi:10.3390/proceedings1040304

Fabrication of Sharp Tip-Separable Microneedle Device for Trans-Dermal Drug Delivery Systems

Hiroshima City University, 3-4-1, Ozuka-Higashi, Asa-Minami-Ku, Hiroshima 731-3194, Japan
Presented at the Eurosensors 2017 Conference, Paris, France, 3–6 September 2017.
*
Author to whom correspondence should be addressed.
Published: 17 August 2017
Download PDF [1392 KB, uploaded 17 August 2017]

Abstract

An alignment mechanism for producing a sharp tip-separable microneedle device for trans-dermal drug delivery systems has been developed. The needle and base parts were placed on a mechanical precision motion stage to align their central axes. The overlapping region between them in the height direction was controlled by inserting a thickness gauge between them. A 400-μm-high sharp tip-separable microneedle device was successfully produced by using the developed alignment mechanism with an accuracy of less than 19 μm. We also demonstrated that it can be used to produce an arrayed tip-separable microneedle device.
Keywords: alignment mechanism; tip-separable microneedle device; trans-dermal drug delivery systems alignment mechanism; tip-separable microneedle device; trans-dermal drug delivery systems
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Nabekura, Y.; Fukuyu, H.; Hasegawa, Y.; Shikida, M. Fabrication of Sharp Tip-Separable Microneedle Device for Trans-Dermal Drug Delivery Systems. Proceedings 2017, 1, 304.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Proceedings EISSN 2504-3900 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top