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Designs 2018, 2(3), 23; https://doi.org/10.3390/designs2030023

Concept Justification of Future 3DPVS and Novel Approach towards its Conceptual Development

School of Engineering, University of South Australia; Mawson Lakes Blvd, Mawson Lakes, SA 5095, Australia
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Received: 29 May 2018 / Revised: 4 July 2018 / Accepted: 5 July 2018 / Published: 8 July 2018
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Abstract

The categorization of cell culture chiefly includes two aspects; one is the dimensionality and another regards the dynamicity. Referring to knowledge of “engineering system evolution”, 2D toward 3D cell culture follows the direction of evolution in dimensionality, and 3D scaffolds with 3DP as its popular fabrication tools has played a role in 3D cell culture applications. Dynamic methods of cell culturing, compared with traditional static means, generally follow the evolution line “static to motional or dynamic”, and vibration has been selected frequently as the suitable tool to achieve the dynamicity of cell culture. Although such a scaffold plus vibration approach has benefited cell culture, there exist significant defects. To mitigate some existing gaps, as well as following further evolutionary trends, the concept of the 3D printed vibratory scaffold (3DPVS) used in cell culture applications is firstly brought out in this study. With 3DPVS, a 3D scaffold in traditional scaffold engineering could potentially evolve into a novel vibratory scaffold which will play significant role in future bioengineering and scaffold engineering. Since 3DPVS’s development remains blank, designers firstly need to propose a high-quality conceptual design; the process of identifying design methodology is challenging since there has been no formal methodology applied for scaffold design. To address these issues, a new design approach is proposed in this paper, which includes an integral development process and focuses on the 3DPVS conceptual stage. The possible methodology and tools to achieve the established conceptual design in following step will be also be discussed. View Full-Text
Keywords: design theory; conceptual design; engineering design process; scaffold design; scaffold innovation; methodology; cell culture; 3D scaffold; dynamic scaffold; 3D static or passive scaffold; vibration; 3D printing; laws of system evolution; 3D printed vibratory scaffold (3DPVS) design theory; conceptual design; engineering design process; scaffold design; scaffold innovation; methodology; cell culture; 3D scaffold; dynamic scaffold; 3D static or passive scaffold; vibration; 3D printing; laws of system evolution; 3D printed vibratory scaffold (3DPVS)
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Yuan, H.; Xing, K.; Hsu, H.-Y. Concept Justification of Future 3DPVS and Novel Approach towards its Conceptual Development. Designs 2018, 2, 23.

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