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Inventions 2018, 3(3), 49; https://doi.org/10.3390/inventions3030049

Cyclic Block Copolymer Microchannel Fabrication and Sealing for Microfluidics Applications

1
Department of Mechanical Engineering, National Central University, Taoyuan City 32001, Taiwan
2
R&D Division, USI Corporation, New Taipei City 224, Taiwan
3
Advanced Materials Business Unit, USI Corporation, Taipei 11492, Taiwan
*
Author to whom correspondence should be addressed.
Received: 16 May 2018 / Revised: 3 July 2018 / Accepted: 13 July 2018 / Published: 16 July 2018
(This article belongs to the Special Issue Microfluidics and Nanofluidics)
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Abstract

High mechanical rigidity, chemical resistance, and ultraviolet-visible light transmissivity of thermoplastics are attractive characteristics in microfluidics because various biomedical microfluidic devices require solvent, acid, or base manipulation, and optical observation or detection. The cyclic block copolymer (CBC) is a new class of thermoplastics with excellent optical properties, low water absorption, favorable chemical resistance, and low density, which make it ideal for use in polymer microfluidic applications. In the polymer microfabrication process, front-end microchannel fabrication and post-end bonding are critical steps that determine the success of polymer microfluidic devices. In this study, for the first time, we verified the performance of CBC created through front-end microchannel fabrication by applying hot embossing and post-end sealing and bonding, and using thermal fusion and ultraviolet (UV)/ozone surface-assist bonding methods. Two grades of CBC were evaluated and compared with two commonly used cyclic olefin polymers, cyclic olefin copolymers (COC), and cyclic olefin polymers (COP). The results indicated that CBCs provided favorable pattern transfer (>99%) efficiency and high bonding strength in microchannel fabrication and bonding procedures, which is ideal for use in microfluidics. View Full-Text
Keywords: cyclic block copolymer; microchannel; hot embossing; thermal bonding; UV/ozone bonding; polymer microfluidics cyclic block copolymer; microchannel; hot embossing; thermal bonding; UV/ozone bonding; polymer microfluidics
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Yen, C.-Y.; Chang, M.-C.O.; Shih, Z.-F.; Lien, Y.-H.; Tsao, C.-W. Cyclic Block Copolymer Microchannel Fabrication and Sealing for Microfluidics Applications. Inventions 2018, 3, 49.

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