Next Article in Journal
Steady Flux Regime During Convective Mixing in Three-Dimensional Heterogeneous Porous Media
Previous Article in Journal
Sinus Hemodynamics in Representative Stenotic Native Bicuspid and Tricuspid Aortic Valves: An In-Vitro Study
Article Menu

Export Article

Open AccessArticle
Fluids 2018, 3(3), 57; https://doi.org/10.3390/fluids3030057

Microparticle Inertial Focusing in an Asymmetric Curved Microchannel

1
Mechatronics Engineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Tuzla, Istanbul 34956, Turkey
2
Center of Excellence for Functional Surfaces and Interfaces for Nano-Diagnostics (EFSUN), Sabanci University SUNUM Nanotechnology Research Center, Sabanci University, Tuzla, Istanbul 34956, Turkey
*
Author to whom correspondence should be addressed.
Received: 30 July 2018 / Accepted: 7 August 2018 / Published: 9 August 2018
View Full-Text   |   Download PDF [2127 KB, uploaded 10 August 2018]   |  

Abstract

Inertial Microfluidics offer a high throughput, label-free, easy to design, and cost-effective solutions, and are a promising technique based on hydrodynamic forces (passive techniques) instead of external ones, which can be employed in the lab-on-a-chip and micro-total-analysis-systems for the focusing, manipulation, and separation of microparticles in chemical and biomedical applications. The current study focuses on the focusing behavior of the microparticles in an asymmetric curvilinear microchannel with curvature angle of 280°. For this purpose, the focusing behavior of the microparticles with three different diameters, representing cells with different sizes in the microchannel, was experimentally studied at flow rates from 400 to 2700 µL/min. In this regard, the width and position of the focusing band are carefully recorded for all of the particles in all of the flow rates. Moreover, the distance between the binary combinations of the microparticles is reported for each flow rate, along with the Reynolds number corresponding to the largest distances. Furthermore, the results of this study are compared with those of the microchannel with the same curvature angle but having a symmetric geometry. The microchannel proposed in this study can be used or further modified for cell separation applications. View Full-Text
Keywords: microfluidics; inertial focusing; fluorescent particle focusing; curvilinear microchannel microfluidics; inertial focusing; fluorescent particle focusing; curvilinear microchannel
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Özbey, A.; Karimzadehkhouei, M.; Alijani, H.; Koşar, A. Microparticle Inertial Focusing in an Asymmetric Curved Microchannel. Fluids 2018, 3, 57.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Fluids EISSN 2311-5521 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top