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Microfluidic Spun Alginate Hydrogel Microfibers and Their Application in Tissue Engineering

Beijing Advanced Innovation Center for Intelligent Robots and Systems, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 10081, China
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Received: 9 February 2018 / Revised: 22 March 2018 / Accepted: 24 March 2018 / Published: 23 April 2018
(This article belongs to the Special Issue Hydrogels in Tissue Engineering)
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Abstract

Tissue engineering is focusing on processing tissue micro-structures for a variety of applications in cell biology and the “bottom-up” construction of artificial tissue. Over the last decade, microfluidic devices have provided novel tools for producing alginate hydrogel microfibers with various morphologies, structures, and compositions for cell cultivation. Moreover, microfluidic spun alginate microfibers are long, thin, and flexible, and these features facilitate higher-order assemblies for fabricating macroscopic cellular structures. In this paper, we present an overview of the microfluidic spinning principle of alginate hydrogel microfibers and their application as micro-scaffolds or scaffolding elements for 3D assembly in tissue engineering. View Full-Text
Keywords: microfluidic spinning; alginate hydrogel microfibers; 3D assembly; tissue engineering microfluidic spinning; alginate hydrogel microfibers; 3D assembly; tissue engineering
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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MDPI and ACS Style

Sun, T.; Li, X.; Shi, Q.; Wang, H.; Huang, Q.; Fukuda, T. Microfluidic Spun Alginate Hydrogel Microfibers and Their Application in Tissue Engineering. Gels 2018, 4, 38.

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