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J. Fungi 2017, 3(3), 40;

Metabolic Interactions between Bacteria and Fungi in Commensal Oral Biofilms

Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), Vrije Universiteit Amsterdam and the University of Amsterdam, Amsterdam, 1081 LA, The Netherlands
Author to whom correspondence should be addressed.
Received: 26 June 2017 / Revised: 10 July 2017 / Accepted: 12 July 2017 / Published: 14 July 2017
(This article belongs to the Special Issue Fungal Biofilms)
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Oral health is more than just the absence of disease. The key to oral health is a diverse microbiome in an ecological balance. The oral microbiota is one of the most complex and diverse microbial communities in the human body. To maintain oral health, balance between the human host and the intrinsic microorganisms is essential. The healthy oral cavity is represented by a great microbial diversity, including both bacteria and fungi. The bacterial microbiome is very well studied. In contrast, fungi inhabiting the oral cavity are often overlooked. All microbial species in the oral cavity form communities which establish a variety of micro-niches and inter- and intra-species interactions. These interactions can be classified into three main groups: physical, chemical and metabolic interactions. Different metabolic interactions are reviewed in this report, among which are the metabolism of sugars, carbon, lactate and oxygen. This review set out with the aim of assessing the importance of metabolic interactions between fungi and bacteria in the healthy oral cavity. View Full-Text
Keywords: oral biofilms; bacterium-fungus interactions; healthy oral cavity; oxygen gradients oral biofilms; bacterium-fungus interactions; healthy oral cavity; oxygen gradients

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Lof, M.; Janus, M.M.; Krom, B.P. Metabolic Interactions between Bacteria and Fungi in Commensal Oral Biofilms. J. Fungi 2017, 3, 40.

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