The Candida albicans Biofilm Matrix: Composition, Structure and Function
AbstractA majority of infections caused by Candida albicans—the most frequent fungal pathogen—are associated with biofilm formation. A salient feature of C. albicans biofilms is the presence of the biofilm matrix. This matrix is composed of exopolymeric materials secreted by sessile cells within the biofilm, in which all classes of macromolecules are represented, and provides protection against environmental challenges. In this review, we summarize the knowledge accumulated during the last two decades on the composition, structure, and function of the C. albicans biofilm matrix. Knowledge of the matrix components, its structure, and function will help pave the way to novel strategies to combat C. albicans biofilm infections. View Full-Text
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Pierce, C.G.; Vila, T.; Romo, J.A.; Montelongo-Jauregui, D.; Wall, G.; Ramasubramanian, A.; Lopez-Ribot, J.L. The Candida albicans Biofilm Matrix: Composition, Structure and Function. J. Fungi 2017, 3, 14.
Pierce CG, Vila T, Romo JA, Montelongo-Jauregui D, Wall G, Ramasubramanian A, Lopez-Ribot JL. The Candida albicans Biofilm Matrix: Composition, Structure and Function. Journal of Fungi. 2017; 3(1):14.Chicago/Turabian Style
Pierce, Christopher G.; Vila, Taissa; Romo, Jesus A.; Montelongo-Jauregui, Daniel; Wall, Gina; Ramasubramanian, Anand; Lopez-Ribot, Jose L. 2017. "The Candida albicans Biofilm Matrix: Composition, Structure and Function." J. Fungi 3, no. 1: 14.
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