Next Article in Journal
Contralateral Orbital Mucocele as a Complication of Unilateral Nasal Polyposis
Previous Article in Journal
Sinusitis and Respiratory Disease at Pediatric Age
Article Menu

Export Article

Open AccessArticle
Sinusitis 2016, 1(1), 92-98; doi:10.3390/sinusitis1010092

Are Chronic Rhinosinusitis and Paranasal Sinus Pneumatization Related?

1
Department of Otolaryngology-Head and Neck Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USA
2
Department of Otorhinolaryngology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA
3
Ochsner Clinical School, University of Queensland School of Medicine, New Orleans, LA 70121, USA
*
Author to whom correspondence should be addressed.
Academic Editor: César Picado
Received: 8 October 2016 / Revised: 11 November 2016 / Accepted: 21 November 2016 / Published: 28 November 2016
View Full-Text   |   Download PDF [1500 KB, uploaded 20 December 2016]   |  

Abstract

The relationship between paranasal sinus pneumatization and chronic rhinosinusitis (CRS) without cystic fibrosis is not well understood. Previous investigations have confirmed sinus hypoplasia in cystic fibrosis (CF) patients. This study compares paranasal sinus pneumatization of CRS patients to unaffected controls to determine if there is an analogous effect to that seen in CF. 591 sinus computed tomography (CT) scans, comprised of 303 adolescents (age 13–18) and 288 adults (age > 18), were analyzed for Lund-MacKay and Assessment of Pneumatization of the Paranasal Sinuses (APPS) scores. The APPS score is validated for measuring the extent of sinus pneumatization. A diagnosis of CRS and CRS phenotype was determined from the medical record. The mean APPS score for patients with a diagnosis of CRS was 10.61 (n = 111) compared to 9.62 (n = 448) for unaffected controls (p = 0.001). This was significant in adult (p = 0.021) and adolescent subgroups (p = 0.035). Sinus pneumatization did not differ according to CRS phenotype (p = 0.699). This suggests that there is not analogous anatomical sinus variation between CRS and CF, and that the mechanisms underlying sinus hypoplasia in CF may not be universal in patients with other types of sinus inflammation. View Full-Text
Keywords: pneumatization; paranasal sinuses; computed tomography; chronic rhinosinusitis; cystic fibrosis pneumatization; paranasal sinuses; computed tomography; chronic rhinosinusitis; cystic fibrosis
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Marino, M.J.; Riley, C.A.; Wu, E.L.; Weinstein, J.E.; McCoul, E.D. Are Chronic Rhinosinusitis and Paranasal Sinus Pneumatization Related? Sinusitis 2016, 1, 92-98.

Show more citation formats Show less citations formats

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Sinusitis EISSN 2309-107X Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top