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Systemic Inflammation in the Genesis of Frailty and Sarcopenia: An Overview of the Preventative and Therapeutic Role of Exercise and the Potential for Drug Treatments
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Geriatrics 2017, 2(1), 9; doi:10.3390/geriatrics2010009

Response to Pulmonary Rehabilitation in Older People with Physical Frailty, Sarcopenia and Chronic Lung Disease

Royal Bournemouth & Christchurch Hospitals NHS Foundation Trust, Castle Lane East, Bournemouth BH7 7DW, UK
Bournemouth University, Poole BH12 5BB, UK
Author to whom correspondence should be addressed.
Academic Editors: Joseph S. K. Kwan and Ralf Lobmann
Received: 26 October 2016 / Revised: 4 January 2017 / Accepted: 20 January 2017 / Published: 22 January 2017
(This article belongs to the Special Issue Frailty and Sarcopenia in Old Age)
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Frailty and sarcopenia are two important clinical syndromes associated with the ageing process, with a high risk of morbidity and mortality. Patients with chronic disease have been shown to have an accelerated decline into a frail state, with patients with both chronic lung disease and frailty having a higher mortality than those with frailty alone. Pulmonary rehabilitation has been found to be an effective intervention in patients with chronic obstructive pulmonary disease (COPD), yet the effect of frailty on this as intervention remains unclear. A narrative literature search of PubMed, Medline complete and the Cochrane library was performed by the reviewers using predefined criteria. Only 3 studies met the selection criteria and were reviewed. These studies highlighted that, although completion rates are lower in patients with both COPD and frailty, pulmonary rehabilitation remains effective as an intervention in this subgroup of patients, with up to 61% of frail patients no longer meeting frailty criteria after completion of a pulmonary rehabilitation programme. View Full-Text
Keywords: frailty; sarcopenia; chronic obstructive pulmonary disease; pulmonary rehabilitation frailty; sarcopenia; chronic obstructive pulmonary disease; pulmonary rehabilitation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Attwell, L.; Vassallo, M. Response to Pulmonary Rehabilitation in Older People with Physical Frailty, Sarcopenia and Chronic Lung Disease. Geriatrics 2017, 2, 9.

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