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Open AccessCase Report
Vet. Sci. 2017, 4(3), 45; https://doi.org/10.3390/vetsci4030045

Complete Resolution of a Recurrent Canine Anal Sac Squamous Cell Carcinoma with Palliative Radiotherapy and Carboplatin Chemotherapy

Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK
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Author to whom correspondence should be addressed.
Academic Editor: Ellen (Liz) Sparger
Received: 9 August 2017 / Revised: 8 September 2017 / Accepted: 11 September 2017 / Published: 14 September 2017
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Abstract

Anal sac squamous cell carcinoma (SCC) is a rare tumor in dogs. Only eight cases have been described in the literature, and previous reports of treatment only describe surgery or palliative treatment with non-steroidal anti-inflammatory drugs. We report a case of a 12-year-old female neutered Labrador with locally advanced anal sac SCC. The dog was treated with four cycles of carboplatin 300 mg/m2 and four weekly fractions of 8.5 Gy radiation. The dog achieved a complete response, and one year later the dog is still alive and well with no evidence of tumor recurrence. Radiotherapy in combination with carboplatin chemotherapy was effective in the long-term control of this rare disease. View Full-Text
Keywords: anal sac squamous cell carcinoma; carboplatin; radiotherapy anal sac squamous cell carcinoma; carboplatin; radiotherapy
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Giuliano, A.; Dobson, J.; Mason, S. Complete Resolution of a Recurrent Canine Anal Sac Squamous Cell Carcinoma with Palliative Radiotherapy and Carboplatin Chemotherapy. Vet. Sci. 2017, 4, 45.

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