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Bioengineering 2017, 4(1), 18;

Antioxidant Activity of SOD and Catalase Conjugated with Nanocrystalline Ceria

Department of Bioengineering, Clemson University, 301 Rhodes Hall, Clemson, SC 29634, USA
Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Leninskii pr. 31, 119991 Moscow, Russia
Institute for Biological Interfaces of Engineering, Clemson University, 301 Rhodes Hall, Clemson, SC 29634, USA
Authors to whom correspondence should be addressed.
Academic Editor: Frank Alexis
Received: 23 December 2016 / Revised: 11 February 2017 / Accepted: 22 February 2017 / Published: 25 February 2017
(This article belongs to the Special Issue Nanoparticle Interaction with the Biological Milieu)
View Full-Text   |   Download PDF [1278 KB, uploaded 25 February 2017]   |  


Interactions of nanoparticles with biological matter—both somatically and in nature—draw scientists’ attention. Nanoparticulate systems are believed to be our saviors, acting as versatile drug delivery vehicles. However, they can also cause life-threatening bodily damage. One of the most important properties of nanocrystalline cerium dioxide is its antioxidant activity, which decreases the abundance of reactive oxygen species during inflammation. In this paper, we report on synergistic effects of inorganic cerium oxide (IV) nanoparticles conjugated with the antioxidative enzymes superoxide dismutase and catalase on scavenging oxygen and nitrogen radicals. View Full-Text
Keywords: nanoceria; antioxidants; superoxide dismutase nanoceria; antioxidants; superoxide dismutase

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Gil, D.; Rodriguez, J.; Ward, B.; Vertegel, A.; Ivanov, V.; Reukov, V. Antioxidant Activity of SOD and Catalase Conjugated with Nanocrystalline Ceria. Bioengineering 2017, 4, 18.

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