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Medicines 2014, 1(1), 56-63;

Acupoint Activation: Response in Microcirculation and the Role of Mast Cells

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie, Dongzhimennei, Beijing 100700, China
Research Unit for Complementary and Integrative Laser Medicine, Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine, and TCM Research Center Graz, Medical University of Graz, Auenbruggerplatz 29, Graz 8036, Austria
Authors to whom correspondence should be addressed.
Received: 14 October 2014 / Revised: 10 November 2014 / Accepted: 13 November 2014 / Published: 20 November 2014
(This article belongs to the Special Issue Feature Papers)
View Full-Text   |   Download PDF [112 KB, uploaded 20 November 2014]   |  


Background: According to Traditional Chinese Medicine (TCM) theory, acupuncture effects are based on the integrity function of meridians. Meridians are thought to regulate body function through the normal flow of qi and/or blood. Disturbances in this flow are thought to cause disease, and acupuncture techniques are believed to cure disease by regulating this flow. However, it is still difficult to understand the exact meaning of qi and to evaluate the activation of meridians. Thus, more and more attention has been focused on the relationship of acupuncture and circulation. Methods: In this narrative review, the authors focus on the state of the art in acupoint activation, microcirculation response, and on investigation of mast cells, based on current literature research. Results: Altogether, 52 references are cited and discussed critically. A schematic diagram of the relationship between acupuncture stimulation, changes of microcirculation and mast cells is presented as result. Conclusion: The block diagram presented in this review article shows that mast cells might play an important role in circulation response after acupoint stimulation. View Full-Text
Keywords: microcirculation; acupuncture point; mast cells microcirculation; acupuncture point; mast cells

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Wang, G.; Litscher, D.; Tian, Y.; Gaischek, I.; Jia, S.; Wang, L.; Zhang, W.; Litscher, G. Acupoint Activation: Response in Microcirculation and the Role of Mast Cells. Medicines 2014, 1, 56-63.

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