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Inorganics 2015, 3(2), 139-154; doi:10.3390/inorganics3020139

Gilded Hope for Medicine

1
Department of Chemistry, University of Sharjah, Sharjah 27272, United Arab Emirates
2
Department of Chemistry, Blinn College, Bryan, TX 77805, USA
3
Department of Chemistry, Delaware State University, 1200 N. DuPont Highway, Dover, DE, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Antonio Laguna
Received: 30 January 2015 / Revised: 13 April 2015 / Accepted: 15 April 2015 / Published: 15 May 2015
(This article belongs to the Special Issue Frontiers in Gold Chemistry)
View Full-Text   |   Download PDF [2335 KB, uploaded 15 May 2015]   |  

Abstract

Gold is emerging as a potential therapeutic agent in the treatment of arthritis, cancer and AIDS. The therapeutic mechanism of arthritic gold drugs and their modification in the presence of stomach hydrochloric acid, in the joints, and in the presence of mild and strong oxidizing agents is a matter of debate. It is believed that gold affects the entire immune response and reduces its potency and limits its oxidizing nature. DNA apparently is not the main target of gold in cancer treatment. Rheumatoid arthritis, cancer, heart diseases and recently AIDS have all been targeted with gold nanoparticles therapy. The era of gold nanoparticles started with cancer imaging and treatment studies. Gold nanoparticles have emerged as smart drug vehicles. View Full-Text
Keywords: gold drugs; gold nanoparticles; rheumatoid arthritis; chrysotherapy; cancer; HIV gold drugs; gold nanoparticles; rheumatoid arthritis; chrysotherapy; cancer; HIV
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Naggar, M.E.; Shehadi, I.; Abdou, H.E.; Mohamed, A.A. Gilded Hope for Medicine. Inorganics 2015, 3, 139-154.

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