Next Article in Journal / Special Issue
Insulin Resistance and NAFLD: A Dangerous Liaison beyond the Genetics
Previous Article in Journal
Assessment of Sleep in Children with Autism Spectrum Disorder
Previous Article in Special Issue
Gut–Liver Axis Derangement in Non-Alcoholic Fatty Liver Disease
Article Menu

Export Article

Open AccessReview
Children 2017, 4(8), 73; doi:10.3390/children4080073

Imaging Features of Non-Alcoholic Fatty Liver Disease in Children and Adolescents

Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, V.le Regina Elena 324 00161 Rome, Italy
Author to whom correspondence should be addressed.
Received: 22 May 2017 / Revised: 30 July 2017 / Accepted: 31 July 2017 / Published: 11 August 2017
(This article belongs to the Special Issue Pediatric Nonalcoholic Fatty Liver Disease)
View Full-Text   |   Download PDF [2199 KB, uploaded 11 August 2017]   |  


Non-invasive diagnosis and quantification of liver steatosis is important to overcome limits of liver biopsy, in order to follow up patients during their therapy and to establish a reference standard that can be used in clinical trials and longitudinal studies. Imaging offers several methods in this setting: ultrasound, which is the cheapest technique and easy to perform; magnetic resonance spectroscopy (MRS), which reflects the real content of triglycerides in a specific volume; and proton density fat fraction (PDFF) magnetic resonance, which is a simple method that reflects the distribution of the fat in the whole liver. Other techniques include ultrasound elastography (EUS) and magnetic resonance elastrography (MRE), which can evaluate the progression of non-alcoholic fatty liver disease (NAFLD) into non-alcoholic steato-hepatitis (NASH) and cirrhosis, by quantifying liver fibrosis. View Full-Text
Keywords: NAFLD; ultrasound; proton density magnetic resonance; magnetic resonance spectroscopy NAFLD; ultrasound; proton density magnetic resonance; magnetic resonance spectroscopy

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Di Martino, M.; Koryukova, K.; Bezzi, M.; Catalano, C. Imaging Features of Non-Alcoholic Fatty Liver Disease in Children and Adolescents. Children 2017, 4, 73.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Children EISSN 2227-9067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top