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Children 2017, 4(4), 28; doi:10.3390/children4040028

Comparison of CPAP and HFNC in Management of Bronchiolitis in Infants and Young Children

Pediatric Department, Hospital of South West Jutland, Finsensgade 35, 6700 Esbjerg, Denmark
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Academic Editor: Sari A. Acra
Received: 11 February 2017 / Revised: 26 March 2017 / Accepted: 11 April 2017 / Published: 20 April 2017
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Abstract

Continuous positive airway pressure (CPAP) has been used in infants with bronchiolitis for decades. Recently, high flow nasal cannula (HFNC) therapy was introduced We conducted a retrospective study of treatment with CPAP vs. HFNC between 2013 and 2015, comparing the development in respiratory rate, fraction of inspired oxygen (FiO2) and heart rate, treatment failure, duration of treatment, and length of hospital stay. A sample size of 49 children were included. Median age was 1.9 months. Median baseline pCO2 was 7.4 kPa in both groups, respiratory rate per minute was 57 vs. 58 (CPAP vs. HFNC). Respiratory rate decreased faster in the CPAP group (p < 0.05). FiO2 decreased in the CPAP group and increased in the HFNC group during the first 12 h, whereafter it decreased in both groups. (p < 0.01). Heart rate development was similar in both groups. Twelve children (55%) changed systems from HFNC to CPAP due to disease progression. There was no difference in length of treatment, hospital stay, or transmission to intensive care unit between the groups. CPAP was more effective than HFNC in decreasing respiratory rate (RR) and FiO2. No differences were observed in length of treatment or complications. Further studies should be conducted to compare the efficacy of the two treatments of bronchiolitis, preferably through prospective randomized trials. View Full-Text
Keywords: bronchiolitis; non-invasive ventilation; continuous positive airway pressure (CPAP); high flow nasal cannula (HFNC); children bronchiolitis; non-invasive ventilation; continuous positive airway pressure (CPAP); high flow nasal cannula (HFNC); children
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Pedersen, M.B.; Vahlkvist, S. Comparison of CPAP and HFNC in Management of Bronchiolitis in Infants and Young Children. Children 2017, 4, 28.

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