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Open AccessCase Report
Children 2017, 4(11), 94; https://doi.org/10.3390/children4110094

Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report

1
Department of Pediatric Hematology Oncology, Zahraa University Hospital, Beirut 1131, Lebanon
2
Department of Pediatric Hematology Oncology, Faculty of Medical Sciences, Lebanese University, Beirut 1131, Lebanon
*
Author to whom correspondence should be addressed.
Received: 14 September 2017 / Revised: 1 November 2017 / Accepted: 1 November 2017 / Published: 3 November 2017
(This article belongs to the Section Oncology and Hematology)
View Full-Text   |   Download PDF [156 KB, uploaded 3 November 2017]

Abstract

Autoimmune hemolytic anemia is a rare hematologic entity in children. Etiologies are mainly viruses or bacteria. We describe here a case of severe warm autoimmune hemolytic anemia (IgG- and C3d-positive direct antiglobulin test) in an immunocompetent 6-month-old infant with acute Cytomegalovirus infection that responded well to corticotherapy and intraveneous immunoglobulins without using blood component transfusion. This case demonstrates the importance of recognizing CMV in infantile Autoimmune Hemolytic Anemia, especially because hemolysis can be severe and lethal. View Full-Text
Keywords: autoimmune hemolytic anemia; direct antiglobulin testing; cytomegalovirus autoimmune hemolytic anemia; direct antiglobulin testing; cytomegalovirus
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Khalifeh, H.K.; Mourad, Y.M.; Chamoun, C.T. Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report. Children 2017, 4, 94.

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