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Healthcare 2017, 5(4), 92; https://doi.org/10.3390/healthcare5040092

The Impact of Hemodialysis on Spatio-Temporal Characteristics of Gait and Role of Exercise: A Systematic Review

1
London Health Sciences Center, London, ON N6G 5A5, Canada
2
Department of Physiotherapy, Western University, London, ON N6G 1H1, Canada
*
Author to whom correspondence should be addressed.
Academic Editors: Joanne Reid and Helen Noble
Received: 13 November 2017 / Revised: 28 November 2017 / Accepted: 30 November 2017 / Published: 5 December 2017
(This article belongs to the Special Issue The Socio-Economic Impact of End Stage Kidney Disease)
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Abstract

Background: People with end-stage kidney disease (ESKD) on hemodialysis (HD) commonly have functional impairments. The purpose of this systematic review was to evaluate the effect of HD on spatio-temporal characteristics of gait, and effect of exercise on these parameters. Methods: Electronic databases were searched to identify relevant citations. Extracted data was computed using a random effects model for means (Hedges’ and 95% confidence interval (CI). Results: 27 studies met inclusion criteria. Mean values: gait speed (GS)—1.0 m/s (CI: 0.9–1.1 m/s; 16 studies), fast walking speed (FWS)—1.5 m/s (CI: 1.3–1.6 m/s; 7 studies), timed get-up & go test (TUG) —6.8 s (CI: 6.1–7.5 s; 2 studies), walk tests (WT) 193.0 s (CI: 116.0–270.0; 5 studies), 6 min-walk-test (6MWT)—386.6 m (CI: 243.2–530.0 m; 11 studies). 4 studies compared participants on HD with normal controls and 10 studies evaluated the effect of nutrition/exercise. Conclusions: Compared to age-matched populations, people with ESKD/HD had significantly slower GS and reduced walk distances; with intervention, the change in the distance walked was significant. Further research is required to evaluate the effect of HD on gait parameters, and the type of exercise/nutrition that will lead to meaningful changes. View Full-Text
Keywords: gait speed; 6 min walk test; timed up-and-go test; hemodialysis; end-stage kidney disease gait speed; 6 min walk test; timed up-and-go test; hemodialysis; end-stage kidney disease
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Sawant, A.; Overend, T. The Impact of Hemodialysis on Spatio-Temporal Characteristics of Gait and Role of Exercise: A Systematic Review. Healthcare 2017, 5, 92.

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